Spheroids, Cellular

Spherical, heterogeneous aggregates of proliferating, quiescent, and necrotic cells in culture that retain three-dimensional architecture and tissue-specific functions. The ability to form spheroids is a characteristic trait of CULTURED TUMOR CELLS derived from solid TUMORS. Cells from normal tissues can also form spheroids. They represent an in-vitro model for studies of the biology of both normal and malignant cells. (From Bjerkvig, Spheroid Culture in Cancer Research, 1992, p4)

Year introduced: 2004(1996)

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Tree Number(s): A11.251.800

MeSH Unique ID: D018874

Entry Terms:

• Cellular Spheroid
• Cellular Spheroids
• Spheroid, Cellular
• Multicellular Spheroids
• Multicellular Spheroid
• Spheroid, Multicellular
• Spheroids, Multicellular

Previous Indexing:

• Cells, Cultured (1972-1995)
• Tissue Culture (1966-1971)
• Tumor Cells, Cultured (1988-1995)

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Anatomy Category
Cells
Cells, Cultured
Spheroids, Cellular