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The reproductive organ (GONADS) in female animals. In vertebrates, the ovary contains two functional parts: the OVARIAN FOLLICLE for the production of female germ cells (OOGENESIS); and the endocrine cells (GRANULOSA CELLS; THECA CELLS; and LUTEAL CELLS) for the production of ESTROGENS and PROGESTERONE.


Polycystic Ovary Syndrome

A complex disorder characterized by infertility, HIRSUTISM; OBESITY; and various menstrual disturbances such as OLIGOMENORRHEA; AMENORRHEA; ANOVULATION. Polycystic ovary syndrome is usually associated with bilateral enlarged ovaries studded with atretic follicles, not with cysts. The term, polycystic ovary, is misleading.

Year introduced: 1985


Ovarian Neoplasms

Tumors or cancer of the OVARY. These neoplasms can be benign or malignant. They are classified according to the tissue of origin, such as the surface EPITHELIUM, the stromal endocrine cells, and the totipotent GERM CELLS.


Granulosa cell tumor of the ovary [Supplementary Concept]

A rare type of ovarian cancer and SEX CHORD STROMAL TUMOR that usually occurs in adults and causes elevated levels of ESTROGEN in a woman's body. The most common symptoms include early puberty for affected young girls, an increase in abdomen size or irregularities of menstrual cycles in premenopausal women, and abnormal uterine bleeding in postmenopausal women.

Date introduced: August 25, 2010


Primary Ovarian Insufficiency

Cessation of ovarian function after MENARCHE but before the age of 40, without or with OVARIAN FOLLICLE depletion. It is characterized by the presence of OLIGOMENORRHEA or AMENORRHEA, elevated GONADOTROPINS, and low ESTRADIOL levels. It is a state of female HYPERGONADOTROPIC HYPOGONADISM. Etiologies include genetic defects, autoimmune processes, chemotherapy, radiation, and infections. The most commonly known genetic cause is the expansion of a CGG repeat to 55 to 199 copies in the 5' untranslated region in the X-linked FMR1 gene.

Year introduced: 2011(1992)



The reproductive organs of plants.

Year introduced: 2003


Brenner Tumor

A smooth, solid or cystic fibroepithelial (FIBROEPITHELIAL NEOPLASMS) tumor, usually found in the OVARIES but can also be found in the adnexal region and the KIDNEYS. It consists of a fibrous stroma with nests of epithelial cells that sometimes resemble the transitional cells lining the urinary bladder. Brenner tumors generally are benign and asymptomatic. Malignant Brenner tumors have been reported.


Androblastoma of ovary [Supplementary Concept]

A Sertoli-Leydig Cell Tumor that arises in the ovary. Release of male sex hormones by the tumor cells may cause VIRILISM.

Date introduced: August 25, 2010


ovary maturating parsin protein, Locusta migratoria [Supplementary Concept]

from the nervous corpora cardiaca of the African locust Locusta migratoria migratorioides; amino acid sequence given in first source; RN given is for 26-L-Ser

Date introduced: February 12, 1992


MGARP protein, mouse [Supplementary Concept]

RefSeq NM_026358

Date introduced: April 24, 2006


Nohma protein, mouse [Supplementary Concept]

GenBank AY626343

Date introduced: January 4, 2006


Rhox8 protein, mouse [Supplementary Concept]

RefSeq NM_001004193

Date introduced: November 24, 2004


MGARP protein, human [Supplementary Concept]

283 amino acid residues, 29.9 k Da; RefSeq NM_032623

Date introduced: August 6, 2004


Og2x protein, mouse [Supplementary Concept]

critical for specifying an oocyte-restricted gene expression pattern essential for postnatal follicle development; GenBank AY061761; RefSeq NM_130869

Date introduced: June 11, 2002


sov protein, Drosophila [Supplementary Concept]

RefSeq NM_132120.2

Date introduced: April 3, 2019

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