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Items: 1 to 20 of 21

1.

MCF-7 Cells

An estrogen responsive cell line derived from a patient with metastatic human breast ADENOCARCINOMA (at the Michigan Cancer Foundation.)

Year introduced: 2013

2.

NL-608 [Supplementary Concept]

a nutlin 3 analog that induces apoptosis in human breast cancer MCF-7 cells

Date introduced: February 21, 2013

3.

aspartyl-methionyl-prolyl-glycyl-threonyl-valyl-leucyl-proline [Supplementary Concept]

an MCF-7 cancer cell-binding peptide

Date introduced: February 23, 2012

4.

Hyul-Tong-Ryung [Supplementary Concept]

commercially available mixure of 12 different Chinese plants, listed in first source; inhibits PMA-induced cellular invasion of MCF-7 human breast carcinoma cells

Date introduced: March 8, 2011

5.

lapiferin [Supplementary Concept]

from Ferula vesceritensis, induces apoptosis pathway in MCF-7 breast cancer cells; structure in first source

Date introduced: May 4, 2010

6.

terricollene A [Supplementary Concept]

from the endolichenic fungus Neurospora terricola; showed modest cytotoxicity against the human tumor cell lines HeLa and MCF-7; structure in first source

Date introduced: November 24, 2009

7.

amamistatin A [Supplementary Concept]

showed antitumor activity against MCF-7 and PC-3 human tumor cells; structure in first source

Date introduced: June 7, 2007

8.

amamistatin B [Supplementary Concept]

showed antitumor activity against MCF-7 and PC-3 human tumor cells; structure in first source

Date introduced: June 7, 2007

9.

dohevanil [Supplementary Concept]

induces apoptosis in MCF-7 cells; structure in first source

Date introduced: April 12, 2006

10.

chlorambucil-N-(2-(4-(4-bis(2-chloroethyl)aminophenyl)butyryl)aminoethyl)-5-(4-amidinophenyl)-2-furancarboxamide hydrochloride [Supplementary Concept]

an analogue of chlorambucil is a stronger inhibitor of protein and DNA synthesis in MCF-7 cells than is the parent drug

Date introduced: June 13, 2005

11.

MACROD1 protein, human [Supplementary Concept]

is a gene cloned from lymphocytic cells, and its function is not known. The expression level of LRP16 mRNA was up-regulated by estrogen in breast cancer MCF-7 cells based on the computed aided serial analysis of gene expression (SAGE) analysis; RefSeq NM_014067

Date introduced: September 2, 2003

12.

octreotide-conjugated paclitaxel [Supplementary Concept]

created by coupling taxol-succinate to the amino-terminal end of octreotide which retains the biological activity of taxol in inducing formation of tubulin bundles, eventually causing apoptosis of MCF-7 cells; structure in first source

Date introduced: August 31, 2000

13.

Ber-EP4 monoclonal antibody [Supplementary Concept]

a commercially-available MAb generated by immunizing mice with cells from the MCF-7 breast carcinoma cell line; distinguishes epithelial mesothelioma from adenocarcinoma

Date introduced: March 19, 1999

14.

RU 58668 [Supplementary Concept]

a steroidal antiestrogen; induces a long-term regression of human mammary MCF-7 tumors implanted in nude mice; structure given in first source

Date introduced: April 29, 1994

15.

7-benzylamino-6-chloro-2-piperazino-4-pyrrolidinopteridine [Supplementary Concept]

inibits growth of B16 melanoma & MCF-7 mammary carcinoma cells

Date introduced: July 27, 1993

16.

ZK 119010 [Supplementary Concept]

possess both antagonistic and agonistic potencies in MCF-7 cells

Date introduced: December 11, 1991

17.

RU 39411 [Supplementary Concept]

inhibits tamoxifen-stimulated growth of an MCF-7 tumor variant; structure given in first source

Date introduced: August 23, 1989

18.

LOC377776 protein, human [Supplementary Concept]

MW 24K estrogen-associated protein from endometrium; may serve as marker for endometrial development; srp27 was first described as an estrogen-induced 24K protein in MCF-7 cells; present in both normal stroma & stromal sarcoma

Date introduced: June 5, 1986

19.

estrogen regulated protein [Supplementary Concept]

human proteins are from the MCF-7 breast tumor cell line; see also records for estrogen regulated proteins TTF1 protein, human and HSPB1 protein, human

Date introduced: September 7, 1983

20.

LYF-11 [Supplementary Concept]

inhibits JAK2-STAT3 signaling pathway in MCF-7 cells

Date introduced: May 18, 2018

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