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1.

Burkitt Lymphoma

A form of undifferentiated malignant LYMPHOMA usually found in central Africa, but also reported in other parts of the world. It is commonly manifested as a large osteolytic lesion in the jaw or as an abdominal mass. B-cell antigens are expressed on the immature cells that make up the tumor in virtually all cases of Burkitt lymphoma. The Epstein-Barr virus (HERPESVIRUS 4, HUMAN) has been isolated from Burkitt lymphoma cases in Africa and it is implicated as the causative agent in these cases; however, most non-African cases are EBV-negative.

Year introduced: 1998 (1968)

2.

ribosomal protein L3 [Supplementary Concept]

acidic protein of the 60 S ribosome subunit

Date introduced: May 26, 1981

3.

UCHL3 protein, human [Supplementary Concept]

RefSeq NM_006002

Date introduced: August 4, 2006

4.

LIM homeobox protein 8 [Supplementary Concept]

RefSeq NM_001001933

Date introduced: July 9, 1998

5.

Onchocerca volvulus L3 cysteine protease [Supplementary Concept]

required for molting of O. volvulus third stage larvae; amino acid sequence given in first source; GenBank U71150

Date introduced: January 10, 1997

6.

MRPL3 protein, human [Supplementary Concept]

RefSeq NM_007208

Date introduced: May 30, 2012

8.

UCHL3 protein, mouse [Supplementary Concept]

a deubiquitinizing enzyme; regulates apical membrane recycling of ENaC; GenBank AB033370

Date introduced: February 28, 2008

9.

Capn3 protein, rat [Supplementary Concept]

RefSeq NM_017117

Date introduced: November 2, 2004

10.

eurocrine L3 [Supplementary Concept]

a heat-killed bacille Calmette-Guerin (H-kBCF) nasal vaccine

Date introduced: June 16, 2004

11.

ASP-2 protein, Ancylostoma ceylanicum [Supplementary Concept]

Ancylostoma-secreted protein (ASP) cloned from infective third-stage larvae (L3) of the hookworm A. ceylanicum; GenBank AAC35986

Date introduced: April 22, 2004

12.

ASP-1 protein, Ancylostoma ceylanicum [Supplementary Concept]

Ancylostoma-secreted protein (ASP) cloned from infective third-stage larvae (L3) of the hookworm A. ceylanicum; GenBank AAC47001

Date introduced: April 22, 2004

13.

LMB89 protocol [Supplementary Concept]

chemotherapy protocol consisting of above cpds for the treatment of B-cell lymphomas and L3 leukemia

Date introduced: June 22, 2001

14.

KLK9 protein, human [Supplementary Concept]

RefSeq NM_012315

Date introduced: July 19, 2000

15.

ALT-1 protein, Onchocerca volvulus [Supplementary Concept]

L3-specific larval antigen isolated from Onchocerca volvulus; amino acid sequence in first source; GenBank U96176 and AF044952

Date introduced: February 8, 1999

16.

baritone L3 [Supplementary Concept]

Date introduced: July 7, 1998

17.

CCR6 protein, human [Supplementary Concept]

RefSeq NM_004367

Date introduced: June 25, 1997

18.

CAPN3 protein, human [Supplementary Concept]

RefSeq NM_173090

Date introduced: June 2, 1997

19.

L3p40-50 antigen [Supplementary Concept]

a lung-tumor-associated 40-50 kDa antigen defined by a monoclonal antibody (L3)

Date introduced: June 24, 1994

20.

licorice-saponin L3 [Supplementary Concept]

from the roots of Glycyrrhiza uralensis Fischer from Xinjiang, China; structure given in first source

Date introduced: December 18, 1993

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