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  • The following terms were not found in MeSH: KBM, KBM-7.
1.

7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide

7,8,8a,9a-Tetrahydrobenzo(10,11)chryseno (3,4-b)oxirene-7,8-diol. A benzopyrene derivative with carcinogenic and mutagenic activity.

Year introduced: 1991(1987)

2.

Interleukin-7 Receptor alpha Subunit

A low affinity interleukin-7 receptor subunit that combines with the INTERLEUKIN RECEPTOR COMMON GAMMA SUBUNIT to form a high affinity receptor for INTERLEUKIN-7.

Year introduced: 2007(1998)

3.

7-Alkoxycoumarin O-Dealkylase

A drug-metabolizing enzyme found in the hepatic, placental and intestinal microsomes that metabolizes 7-alkoxycoumarin to 7-hydroxycoumarin. The enzyme is cytochrome P-450- dependent.

Year introduced: 1990

4.

Cholesterol 7-alpha-Hydroxylase

A membrane-bound cytochrome P450 enzyme that catalyzes the 7-alpha-hydroxylation of CHOLESTEROL in the presence of molecular oxygen and NADPH-FERRIHEMOPROTEIN REDUCTASE. This enzyme, encoded by CYP7, converts cholesterol to 7-alpha-hydroxycholesterol which is the first and rate-limiting step in the synthesis of BILE ACIDS.

Year introduced: 2003 (1975)

5.

Ataxin-7

A component of the STAGA transcription coactivator-HAT complex that functions in Cone Rod Homeobox Protein (CRX)-dependent gene activation. It also stabilizes MICROTUBULES. CAG repeat expansion in the ATXN-7 coding region is associated with the development of SPINOCEREBELLAR ATAXIA 7.

Year introduced: 2016

6.

Transcription Factor 7-Like 2 Protein

A transcription factor that takes part in WNT signaling pathway. The activity of the protein is regulated via its interaction with BETA CATENIN. Transcription factor 7-like 2 protein plays an important role in the embryogenesis of the PANCREAS and ISLET CELLS.

Year introduced: 2011

7.

Interferon Regulatory Factor-7

An interferon regulatory factor that is induced by INTERFERONS as well as LMP-1 protein from EPSTEIN-BARR VIRUS. IRF-7 undergoes PHOSPHORYLATION prior to nuclear translocation and it activates GENETIC TRANSCRIPTION of multiple interferon GENES.

Year introduced: 2006(1997)

8.

Receptors, Interleukin-7

Cell surface receptors that are specific for INTERLEUKIN-7. They are present on T-LYMPHOCYTES and B-LYMPHOCYTE precursors. The receptors are heterodimeric proteins consisting of the INTERLEUKIN-5 RECEPTOR ALPHA SUBUNIT and the CYTOKINE RECEPTOR COMMON BETA SUBUNIT.

Year introduced: 1999

9.

5,7-Dihydroxytryptamine

Tryptamine substituted with two hydroxyl groups in positions 5 and 7. It is a neurotoxic serotonin analog that destroys serotonergic neurons preferentially and is used in neuropharmacology as a tool.

Year introduced: 1991(1978)

10.

3-Deoxy-7-Phosphoheptulonate Synthase

An enzyme that catalyzes the formation of 7-phospho-2-keto-3-deoxy-D-arabinoheptonate from phosphoenolpyruvate and D-erythrose-4-phosphate. It is one of the first enzymes in the biosynthesis of TYROSINE and PHENYLALANINE. This enzyme was formerly listed as EC 4.1.2.15.

Year introduced: 2007(1975)

11.

Cytochrome P450 Family 7

A cytochrome P450 enzyme family whose members function as steroid 7-alpha hydroxylases.

Year introduced: 2017

12.

Minichromosome Maintenance Complex Component 7

A minichromosome maintenance protein that is a key component of the six member MCM protein complex. It is also found in tightly-bound trimeric complex with MINICHROMOSOME MAINTENANCE COMPLEX COMPONENT 4 and MINICHROMOSOME MAINTENANCE COMPLEX COMPONENT 6.

Year introduced: 2014

13.

NAV1.7 Voltage-Gated Sodium Channel

A voltage-gated sodium channel subtype found widely expressed in nociceptive primary sensory neurons. Defects in the SCN9A gene, which codes for the alpha subunit of this sodium channel, are associated with several pain sensation-related disorders.

Year introduced: 2013

14.

MCF-7 Cells

An estrogen responsive cell line derived from a patient with metastatic human breast ADENOCARCINOMA (at the Michigan Cancer Foundation.)

Year introduced: 2013

15.

Transcription Factor 7-Like 1 Protein

A transcription factor that takes part in WNT signaling pathway where it may play a role in the differentiation of KERATINOCYTES. The transcriptional activity of this protein is regulated via its interaction with BETA CATENIN.

Year introduced: 2011

16.

Retinoblastoma-Binding Protein 7

A retinoblastoma-binding protein that has an affinity for core HISTONES. It is found as a subunit of protein complexes that are in involved in the enzymatic modification of histones including the Mi2 and Sin3 histone deacetylase complexes and the polycomb repressive complex 2.

Year introduced: 2010

17.

Bone Morphogenetic Protein 7

A bone morphogenetic protein that is widely expressed during EMBRYONIC DEVELOPMENT. It is both a potent osteogenic factor and a specific regulator of nephrogenesis.

Year introduced: 2009(1990)

18.

Cyclic Nucleotide Phosphodiesterases, Type 7

A cyclic nucleotide phosphodiesterase subfamily that is highly specific for CYCLIC AMP. Several isoforms of the enzyme type exist, each with its own tissue localization. The isoforms are encoded by at least two genes and are a product of multiple alternative splicing of their mRNAs.

Year introduced: 2008(1998)

19.

Receptor-Like Protein Tyrosine Phosphatases, Class 7

A subclass of receptor-like protein tryosine phosphatases that contain a short extracellular domain, a cytosolic kinase-interaction domain, and single protein tyrosine kinase domain.

Year introduced: 2008

20.

Keratin-7

A type II keratin found associated with KERATIN-19 in ductal epithelia and gastrointestinal epithelia.

Year introduced: 2007(1998)

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