U.S. flag

An official website of the United States government

Format
Items per page

Send to:

Choose Destination

Search results

Items: 1 to 20 of 65555

  • The following terms were not found in MeSH: HUDEP, HUDEP-2.
1.

Homeobox Protein Nkx-2.2

A homeobox-containing transcription factor that functions in INSULIN-SECRETING CELLS. Mutations in the NKX2-2 gene are associated with MATURITY-ONSET DIABETES OF THE YOUNG and OLIGODENDROGLIOMA.

Year introduced: 2022 (1995)

2.

2,2'-Dipyridyl

A reagent used for the determination of iron.

Year introduced: 1991(1977)

3.

Ca(2+) Mg(2+)-ATPase

An enzyme that catalyzes the hydrolysis of ATP and is activated by millimolar concentrations of either Ca(2+) or Mg(2+). Unlike CA(2+)-TRANSPORTING ATPASE it does not require the second divalent cation for its activity, and is not sensitive to orthovanadate. (Prog Biophys Mol Biol 1988;52(1):1). A subgroup of EC 3.6.1.3.

Year introduced: 1993

4.

Nuclear Receptor Subfamily 2, Group C, Member 2

An orphan nuclear receptor that has specificity for hormone response elements found in the promoters of target genes. It binds DNA either as a homodimer or as heterodimer with the closely-related orphan nuclear receptor NUCLEAR RECEPTOR SUBFAMILY 2, GROUP C, MEMBER 1. The protein was originally identified as a TESTES-specific protein and is involved in the regulation of variety of cellular processes, including CELL DIFFERENTIATION; CELL PROLIFERATION; and APOPTOSIS.

Year introduced: 2010

5.

4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid

An inhibitor of anion conductance including band 3-mediated anion transport.

Year introduced: 2001(1994)

6.

5-Amino-3-((5-nitro-2-furyl)vinyl)-1,2,4-oxadiazole

A nitrovinyl furan used as a schistosomicidal agent and proposed for trypanosomiasis, especially Chagas disease.

Year introduced: 2005(1975)

7.

4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid

A non-penetrating amino reagent (commonly called SITS) which acts as an inhibitor of anion transport in erythrocytes and other cells.

Year introduced: 2001(1980)

8.

2H-Benzo(a)quinolizin-2-ol, 2-Ethyl-1,3,4,6,7,11b-hexahydro-3-isobutyl-9,10-dimethoxy-

Proposed catecholamine depletor.

Year introduced: 2005(1988)

9.

Phenylphosphonothioic Acid, 2-Ethyl 2-(4-Nitrophenyl) Ester

An organothiophosphorus cholinesterase inhibitor that is used as an insecticide and as a acaricide.

Year introduced: 2001(1972)

10.

3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester

A dihydropyridine derivative, which, in contrast to NIFEDIPINE, functions as a calcium channel agonist. The compound facilitates Ca2+ influx through partially activated voltage-dependent Ca2+ channels, thereby causing vasoconstrictor and positive inotropic effects. It is used primarily as a research tool.

Year introduced: 1987

11.

Src Homology 2 Domain-Containing, Transforming Protein 2

An SHC-signaling adaptor protein that links GROWTH FACTOR RECEPTORS to SIGNAL TRANSDUCTION PATHWAYS in neurons.

Year introduced: 2017

12.

2-Acetolactate Mutase

An enzyme involved in the biosynthesis of isoleucine and valine. It converts 2-acetolactate into 3-hydroxy-2-oxo-isovalerate. Also acts on 2-hydroxy-2-acetobutyrate to form 2-hydroxy-2-oxo-3-methylvalerate. EC 5.4.99.3.

Year introduced: 1991(1975)

13.

Genes, erbB-2

The erbB-2 gene is a proto-oncogene that codes for the erbB-2 receptor (RECEPTOR, ERBB-2), a protein with structural features similar to the epidermal growth factor receptor. Its name originates from the viral oncogene homolog (v-erbB) which is a truncated form of the chicken erbB gene found in the avian erythroblastosis virus. Overexpression and amplification of the gene is associated with a significant number of adenocarcinomas. The human c-erbB-2 gene is located at 17q21.2.

Year introduced: 1995

14.

Catechol 2,3-Dioxygenase

Catalyzes the oxidation of catechol to 2-hydroxymuconate semialdehyde in the carbazole and BENZOATE degradation via HYDROXYLATION pathways. It also catalyzes the conversion of 3-methylcatechol to cis, cis-2-hydroxy-6-oxohept-2,4-dienoate in the TOLUENE and XYLENE degradation pathway. This enzyme was formerly characterized as EC 1.13.1.2.

Year introduced: 2006(1981)

15.

Interleukin-2 Receptor alpha Subunit

A low affinity interleukin-2 receptor subunit that combines with the INTERLEUKIN-2 RECEPTOR BETA SUBUNIT and the INTERLEUKIN RECEPTOR COMMON GAMMA-CHAIN to form a high affinity receptor for INTERLEUKIN-2.

Year introduced: 2007(2001)

16.

2-Aminoadipate Transaminase

A PYRIDOXAL PHOSPHATE containing enzyme that catalyzes the transfer of amino group of L-2-aminoadipate onto 2-oxoglutarate to generate 2-oxoadipate and L-GLUTAMATE.

Year introduced: 2006(1983)

17.

Phosphofructokinase-2

An allosteric enzyme that regulates glycolysis and gluconeogenesis by catalyzing the transfer of a phosphate group from ATP to fructose-6-phosphate to yield fructose-2,6-bisphosphate, an allosteric effector for the other 6-phosphofructokinase, PHOSPHOFRUCTOKINASE-1. Phosphofructokinase-2 is bifunctional: the dephosphorylated form is a kinase and the phosphorylated form is a phosphatase that breaks down fructose-2,6-bisphosphate to yield fructose-6-phosphate.

Year introduced: 2002

18.

Receptors, Interleukin-2

Receptors present on activated T-LYMPHOCYTES and B-LYMPHOCYTES that are specific for INTERLEUKIN-2 and play an important role in LYMPHOCYTE ACTIVATION. They are heterotrimeric proteins consisting of the INTERLEUKIN-2 RECEPTOR ALPHA SUBUNIT, the INTERLEUKIN-2 RECEPTOR BETA SUBUNIT, and the INTERLEUKIN RECEPTOR COMMON GAMMA-CHAIN.

Year introduced: 1990(1989)

19.

2',3'-Cyclic-Nucleotide Phosphodiesterases

Nucleoside-2',3'-cyclic phosphate nucleotidohydrolase. Enzymes that catalyze the hydrolysis of the 2'- or 3'- phosphate bonds of 2',3'-cyclic nucleotides. Also hydrolyzes nucleoside monophosphates. Includes EC 3.1.4.16 and EC 3.1.4.37. EC 3.1.4.-.

Year introduced: 1994

20.

Bcl-2-Like Protein 11

A BCL-2-like protein that has a C-terminal BCL-2 homology (BH3) domain and forms heterodimers with other BCL-2 FAMILY PROTEINS. It is a strong inducer of APOPTOSIS and ANOIKIS; several isoforms are expressed (BimEL, Bim L, Bim-alpha, Bim-s; and Bim-gamma) that have different potencies for inducing apoptosis.

Year introduced: 2017 (1998)

Format
Items per page

Send to:

Choose Destination

Supplemental Content

Loading ...
Support Center