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A biogenic amine that is found in animals and plants. In mammals, melatonin is produced by the PINEAL GLAND. Its secretion increases in darkness and decreases during exposure to light. Melatonin is implicated in the regulation of SLEEP, mood, and REPRODUCTION. Melatonin is also an effective antioxidant.

Year introduced: 1968(1965)

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Tree Number(s): D03.633.100.473.914.481, D06.472.506

MeSH Unique ID: D008550

Registry Number: JL5DK93RCL

Pharmacologic Action:

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