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A malignant form of astrocytoma histologically characterized by pleomorphism of cells, nuclear atypia, microhemorrhage, and necrosis. They may arise in any region of the central nervous system, with a predilection for the cerebral hemispheres, basal ganglia, and commissural pathways. Clinical presentation most frequently occurs in the fifth or sixth decade of life with focal neurologic signs or seizures.

Year introduced: 1994

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Tree Number(s): C04.557.465.625.600.380.080.335, C04.557.470.670.380.080.335, C04.557.580.625.600.380.080.335

MeSH Unique ID: D005909

Entry Terms:

  • Glioblastomas
  • Astrocytoma, Grade IV
  • Astrocytomas, Grade IV
  • Grade IV Astrocytoma
  • Grade IV Astrocytomas
  • Glioblastoma Multiforme
  • Giant Cell Glioblastoma
  • Giant Cell Glioblastomas
  • Glioblastoma, Giant Cell
  • Glioblastomas, Giant Cell

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