U.S. flag

An official website of the United States government


Send to:

Choose Destination


An organoplatinum complex in which the platinum atom is complexed with 1,2-diaminocyclohexane, and with an oxalate ligand which is displaced to yield active oxaliplatin derivatives. These derivatives form inter- and intra-strand DNA crosslinks that inhibit DNA replication and transcription. Oxaliplatin is an antineoplastic agent that is often administered with FLUOROURACIL and FOLINIC ACID in the treatment of metastatic COLORECTAL NEOPLASMS.

Year introduced: 2019 (1981)

PubMed search builder options


Tree Number(s): D02.257.750

MeSH Unique ID: D000077150

Registry Number: 04ZR38536J

Entry Terms:

  • 1,2-Diamminocyclohexane(trans-1)oxolatoplatinum(II)
  • L-OHP Cpd
  • Platinum(2+) ethanedioate (1R,2R)-1,2-cyclohexanediamine (1:1:1)
  • Oxalato-(1,2-cyclohexanediamine)platinum II
  • Oxaliplatin, (SP-4-2-(1R-trans))-isomer
  • Oxaliplatine
  • 1,2-Diaminocyclohexane Platinum Oxalate
  • 1,2 Diaminocyclohexane Platinum Oxalate
  • Platinum(II)-1,2-cyclohexanediamine Oxalate
  • Cis-oxalato-(trans-l)-1,2-diaminocyclohexane-platinum(II)
  • ACT 078
  • ACT-078
  • ACT078
  • Oxaliplatin, (SP-4-3-(cis))-isomer
  • Eloxatine
  • Eloxatin
  • Oxaliplatin, (SP-4-2-(1S-trans))-isomer

Pharmacologic Action:

Supplemental Content

Loading ...