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Imatinib Mesylate

A tyrosine kinase inhibitor and ANTINEOPLASTIC AGENT that inhibits the BCR-ABL kinase created by chromosome rearrangements in CHRONIC MYELOID LEUKEMIA and ACUTE LYMPHOBLASTIC LEUKEMIA, as well as PDG-derived tyrosine kinases that are overexpressed in gastrointestinal stromal tumors.

Year introduced: 2016 (1996)

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Tree Number(s): D02.065.277.456, D02., D02.455.426.559.389.127.085.465, D03.383.606.405, D03.383.742.349

MeSH Unique ID: D000068877

Registry Number: 8A1O1M485B

Entry Terms:

  • Mesylate, Imatinib
  • Imatinib Methanesulfonate
  • Methanesulfonate, Imatinib
  • STI571
  • STI-571
  • STI 571
  • Gleevec
  • Glivec
  • ST 1571
  • ST1571
  • CGP 57148
  • CGP57148B
  • CGP-57148
  • CGP57148
  • Imatinib
  • Alpha-(4-methyl-1-piperazinyl)-3'-((4-(3-pyridyl)-2-pyrimidinyl)amino)-p-tolu-p-toluidide

Pharmacologic Action:

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