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Cyclin-Dependent Kinase 2

A key regulator of CELL CYCLE progression. It partners with CYCLIN E to regulate entry into S PHASE and also interacts with CYCLIN A to phosphorylate RETINOBLASTOMA PROTEIN. Its activity is inhibited by CYCLIN-DEPENDENT KINASE INHIBITOR P27 and CYCLIN-DEPENDENT KINASE INHIBITOR P21.

Year introduced: 2006(1991)

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Tree Number(s): D08.811.913.696.620.682.700.646.500.750, D12.776.167.200.323, D12.776.476.563.646.500.750

MeSH Unique ID: D051357

Registry Number: EC

Entry Terms:

  • Cyclin Dependent Kinase 2
  • p33cdk2 Kinase
  • CDK2 Protein
  • Cdc2-Related Protein Kinase
  • Cdc2 Related Protein Kinase
  • Cdk2 Protein Kinase

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