MeSH

Tumors or cancer of the human BREAST.

Abnormal accumulation of lymph in the arm, shoulder and breast area associated with surgical treatment (e.g., MASTECTOMY) or radiation treatment of breast cancer.

Year introduced: 2017

Tumors or cancer found specifically in one human BREAST, but not in both.

Year introduced: 2016

Breast neoplasms that do not express ESTROGEN RECEPTORS; PROGESTERONE RECEPTORS; and do not overexpress the NEU RECEPTOR/HER-2 PROTO-ONCOGENE PROTEIN.

Year introduced: 2014

Metastatic breast cancer characterized by EDEMA and ERYTHEMA of the affected breast due to LYMPHATIC METASTASIS and eventual obstruction of LYMPHATIC VESSELS by the cancer cells.

Year introduced: 2011

The phosphoprotein encoded by the BRCA1 gene (GENE, BRCA1). It contains an N-terminal RING FINGER DOMAIN and is a PROTEIN PHOSPHATASE 1 regulatory subunit. In normal cells the BRCA1 protein is localized in the nucleus, whereas in the majority of breast cancer cell lines and in malignant pleural effusions from breast cancer patients, it is localized mainly in the cytoplasm. (Science 1995;270(5237):713,789-91)

Year introduced: 1997

don't confuse with Deleted in Bladder Cancer 1(also known as DBC1); RefSeq NM_021174

Date introduced: March 20, 2008

A nuclear receptor coactivator with specificity for ESTROGEN RECEPTORS and PROGESTERONE RECEPTORS. It contains a histone acetyltransferase activity that may play a role in CHROMATIN REMODELING during the process of nuclear receptor-induced transcription. The coactivator has been found at elevated levels in certain HORMONE-DEPENDENT NEOPLASMS such as those found in BREAST CANCER.

Year introduced: 2010(1997)

A highly phosphorylated 130 kDa protein that associates with ONCOGENE PROTEIN CRK and ONCOGENE PROTEIN SRC. It undergoes tyrosine PHOSPHORYLATION in signaling pathways that regulate CELL MIGRATION and CELL PROLIFERATION.

Year introduced: 2006(2004)

A large, nuclear protein, encoded by the BRCA2 gene (GENE, BRCA2). Mutations in this gene predispose humans to breast and ovarian cancer. The BRCA2 protein is an essential component of DNA repair pathways, suppressing the formation of gross chromosomal rearrangements. (from Genes Dev. 2000;14(11):1400-6)

Year introduced: 2002

Any neoplasms of the male breast. These occur infrequently in males in developed countries, the incidence being about 1% of that in females.

Year introduced: 1995

RefSeq NR_024049

Date introduced: November 2, 2010

RefSeq NM_000059

Date introduced: October 7, 2010

RefSeq NM_052997

Date introduced: April 27, 2006

a mediator of metastasis suppression in breast carcinoma; RefSeq NM_015399

Date introduced: June 27, 2000

RefSeq NM_003087

Date introduced: March 4, 1997

RefSeq NM_001540

Date introduced: December 20, 1988

RefSeq NM_003225

Date introduced: April 17, 1987

A human breast cancer cell line that was derived in 1973 from the MALIGNANT PLEURAL EFFUSION of a patient with stage III BREAST CARCINOMA and was characterized as being of breast cancer origin.

Year introduced: 2023

RefSeq NM_009764

Date introduced: March 17, 2016