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A malignant epithelial tumor with a glandular organization.


Adenocarcinoma in Situ

A lesion with cytological characteristics associated with invasive adenocarcinoma but the tumor cells are confined to the GLANDULAR EPITHELIAL CELLS of origin. Adenocarcinoma in situ of the CERVIX and the LUNG are the most common.

Year introduced: 2015


Adenocarcinoma, Sebaceous

A malignant tumor composed of cells showing differentiation toward sebaceous epithelium. The tumor is solitary, firm, somewhat raised, more or less translucent, and covered with normal or slightly verrucose epidermis. It may be yellow or orange. The face and scalp are the commonest sites. The growth can be slow or rapid but metastasis is uncommon. Surgery cures most of the cases. (From Rook et al., Textbook of Dermatology, 4th ed, pp2403-4)

Year introduced: 1994


Adenocarcinoma, Follicular

An adenocarcinoma of the thyroid gland, in which the cells are arranged in the form of follicles. (From Dorland, 27th ed)

Year introduced: 1994


Adenocarcinoma, Clear Cell

An adenocarcinoma characterized by the presence of varying combinations of clear and hobnail-shaped tumor cells. There are three predominant patterns described as tubulocystic, solid, and papillary. These tumors, usually located in the female reproductive organs, have been seen more frequently in young women since 1970 as a result of the association with intrauterine exposure to diethylstilbestrol. (From Holland et al., Cancer Medicine, 3d ed)

Year introduced: 1994


Adenocarcinoma, Scirrhous

An adenocarcinoma with a hard (Greek skirrhos, hard) structure owing to the formation of dense connective tissue in the stroma. (From Dorland, 27th ed)

Year introduced: 1994


Adenocarcinoma, Mucinous

An adenocarcinoma producing mucin in significant amounts. (From Dorland, 27th ed)

Year introduced: 1994


Adenocarcinoma, Bronchiolo-Alveolar

A carcinoma derived from epithelium of terminal bronchioles, in which the neoplastic tissue extends along the alveolar walls and grows in small masses within the alveoli. Involvement may be uniformly diffuse and massive, or nodular, or lobular. The neoplastic cells are cuboidal or columnar and form papillary structures. Mucin may be demonstrated in some of the cells and in the material in the alveoli, which also includes denuded cells. Metastases in regional lymph nodes, and in even more distant sites, are known to occur, but are infrequent. (From Stedman, 25th ed)

Year introduced: 1994


Adenocarcinoma, Papillary

An adenocarcinoma containing finger-like processes of vascular connective tissue covered by neoplastic epithelium, projecting into cysts or the cavity of glands or follicles. It occurs most frequently in the ovary and thyroid gland. (Stedman, 25th ed)


Adenocarcinoma of Lung

A carcinoma originating in the lung and the most common lung cancer type in never-smokers. Malignant cells exhibit distinct features such as glandular epithelial, or tubular morphology. Mutations in KRAS, EGFR, BRAF, and ERBB2 genes are associated with this cancer.

Year introduced: 2019 (2009)


Carcinoma, Renal Cell

A heterogeneous group of sporadic or hereditary carcinoma derived from cells of the KIDNEYS. There are several subtypes including the clear cells, the papillary, the chromophobe, the collecting duct, the spindle cells (sarcomatoid), or mixed cell-type carcinoma.

Year introduced: 1985


Carcinoma, Acinar Cell

A malignant tumor arising from secreting cells of a racemose gland, particularly the salivary glands. Racemose (Latin racemosus, full of clusters) refers, as does acinar (Latin acinus, grape), to small saclike dilatations in various glands. Acinar cell carcinomas are usually well differentiated and account for about 13% of the cancers arising in the parotid gland. Lymph node metastasis occurs in about 16% of cases. Local recurrences and distant metastases many years after treatment are common. This tumor appears in all age groups and is most common in women. (Stedman, 25th ed; Holland et al., Cancer Medicine, 3d ed, p1240; from DeVita Jr et al., Cancer: Principles and Practice of Oncology, 3d ed, p575)

Year introduced: 1994


Carcinoma, Endometrioid

An adenocarcinoma characterized by the presence of cells resembling the glandular cells of the ENDOMETRIUM. It is a common histological type of ovarian CARCINOMA and ENDOMETRIAL CARCINOMA. There is a high frequency of co-occurrence of this form of adenocarcinoma in both tissues.

Year introduced: 1994


Urachal adenocarcinoma [Supplementary Concept]

A rare adenocarcinoma of the bladder that originates in the URACHUS or its remnants.

Date introduced: August 25, 2010


Jaagsiekte sheep retrovirus

A BETARETROVIRUS that causes pulmonary adenomatosis in sheep (PULMONARY ADENOMATOSIS, OVINE).

Year introduced: 2007, 2001


Adenocarcinoma Of Esophagus [Supplementary Concept]

A malignant GLANDULAR NEOPLASM that originates mostly from BARRETT ESOPHAGUS. Esophageal adenocarcinomas are similar to esophageal SQUAMOUS CELL CARCINOMAS morphologically; tumor cells are usually papillary or tubular. Germline mutations in MSR1, CTHRC1, and ASCC1 have been identified. OMIM: 614266

Date introduced: November 5, 2012


MALAT1 long non-coding RNA, human [Supplementary Concept]

up-regulated in carcinomas; NEAT- noncoding nuclear enriched abundant transcript

Date introduced: March 31, 2011


adenocarcinoma antigen recognized by T cells-1 [Supplementary Concept]

a 60 kDa tumor-rejection antigen recognized by cytotoxic T lymphocytes infiltrating into a lung adenocarcinoma; amino acid sequence in first source; GenBank AY527413 (human)

Date introduced: September 27, 2000


adenocarcinoma antigen recognized by T cells-4 [Supplementary Concept]

a 46 kDa protein expressed in the majority of malignant cells and tissues; amino acid sequence in first source

Date introduced: August 16, 2000

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