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1.

A549 Cells

An immortalized cell line derived from human ADENOCARCINOMA, ALVEOLAR basal epithelial cells isolated from the lungs of a male patient in 1972. The cell line is positive for KERATIN, can synthesize LECITHIN, and contains high levels of POLYUNSATURATED FATTY ACIDS in its PLASMA MEMBRANE. It is used as a model for PULMONARY ALVEOLI function and virus infections, as a TRANSFECTION host, and for PRECLINICAL DRUG EVALUATION.

Year introduced: 2017

2.

diincarvilone B [Supplementary Concept]

from Incarvillea arguta; causes persistent increase in cytoplasmic calcium levels in A549 cells; structure in first source

Date introduced: September 11, 2012

3.

diincarvilone A [Supplementary Concept]

from Incarvillea arguta; causes persistent increase in cytoplasmic calcium levels in A549 cells; structure in first source

Date introduced: September 11, 2012

4.

Rhizoma Smilacinus compound [Supplementary Concept]

inhibits growth of non-small cell lung cancers in A549 cell lines

Date introduced: April 17, 2008

5.

ACTX-6 protein, Agkistrodon acutus [Supplementary Concept]

a cytotoxin from Agkistrodon acutus snake venom that induces apoptosis via Fas pathway in A549 cells

Date introduced: December 10, 2007

6.

Wikyungtang [Supplementary Concept]

inhibits proliferation of A549 human lung cancer cells via inducing apoptosis and suppressing cyclooxygenase-2 activity

Date introduced: November 26, 2004

7.

diisopropylglutathione ester [Supplementary Concept]

protects A549 cells from the cytotoxic effects of sulphur mustard

Date introduced: April 6, 1999

8.

EPS11 compound [Supplementary Concept]

isolated from marine bacterium Bacillus sp; blocks cell adhesion and stimulates anoikis of A549 lung tumor cells

Date introduced: September 27, 2018

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