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link protein [Supplementary Concept]

in nasal cartilage & bovine articular cartilage; interacts with proteoglycan monomers to form aggregate structures; involved in stabilizing the interaction between two other components of cartilage, proteoglycan subunit and hyaluronic acid; UTI-BP(40) is identical to link protein (LP); RefSeq NM_001884 (human), NM_013500 (mouse)

Date introduced: January 1, 1980


SPA4CT protein, recombinant [Supplementary Concept]

consists of an N-terminal signal peptide and A4CT; SPA4CT has a leucylglutamyl link between the two, SPA4CT-DIR has no such link, and SPA4CT-DA has an aspartylalanyl link between the two

Date introduced: September 29, 1999


LINK-A long non-coding RNA, human [Supplementary Concept]

a cytoplasmic lncRNA

Date introduced: June 12, 2016


gamma Catenin

A multi-functional catenin that is highly homologous to BETA CATENIN. Gamma catenin binds CADHERINS and helps link their cytoplasmic tails to ACTIN in the CYTOSKELETON via ALPHA CATENIN. It is also found in DESMOSOMES where it mediates the link between DESMOSOMAL CADHERINS and DESMOPLAKIN.

Year introduced: 2006(1983)


Hapln2 protein, mouse [Supplementary Concept]

a 38 kDa protein expressed in adult brain; RefSeq NM_022031

Date introduced: August 6, 2004


HAPLN4 protein, human [Supplementary Concept]

RefSeq NM_023002

Date introduced: January 15, 2004


Hapln4 protein, mouse [Supplementary Concept]

RefSeq NM_177900

Date introduced: January 15, 2004


isodesmopyridine [Supplementary Concept]

an elastin cross-link; structure in first source

Date introduced: May 25, 2001


desmopyridine [Supplementary Concept]

an elastin cross-link; structure in first source

Date introduced: May 25, 2001


DCLRE1C protein, human [Supplementary Concept]

a DNA double-strand break repair/V(D)J recombination protein, is mutated in human severe combined immune deficiency; GenBank AL360083; RefSeq NM_022487

Date introduced: May 24, 2001


HAPLN2 protein, human [Supplementary Concept]

RefSeq NM_021817

Date introduced: November 20, 2000


Senior Centers

Community centers for older adults and providers of resources for the community. In addition to providing services and activities for older adults that reflect the community's diversity, they link participants with resources offered by other agencies.

Year introduced: 2014


MARVEL Domain-Containing Proteins

A family of proteins that share a domain with a four transmembrane-helix architecture referred to as the MARVEL domain. The MARVEL domain proteins play important role in vesicular trafficking and in the formation of TIGHT JUNCTIONS.

Year introduced: 2013


Electronic Supplementary Materials [Publication Type]

Supporting content or information, such as animation, datasets, multimedia files, video, movies, audio files, text files, or software, which is submitted for publication in an online journal or an online edition of a journal. This information may be referenced in the text of the article with a link to the supplementary data provided. CATALOG: do not use

Year introduced: 2011



An order of stalked, sessile, single-celled EUKARYOTES. They are considered the transitional link between the flagellated protozoa and the SPONGES, the most primitive metazoans.

Year introduced: 2010


beta Catenin

A multi-functional catenin that participates in CELL ADHESION and nuclear signaling. Beta catenin binds CADHERINS and helps link their cytoplasmic tails to the ACTIN in the CYTOSKELETON via ALPHA CATENIN. It also serves as a transcriptional co-activator and downstream component of WNT PROTEIN-mediated SIGNAL TRANSDUCTION PATHWAYS.

Year introduced: 2006(1992)



Dystrophin-associated proteins that play role in the formation of a transmembrane link between laminin-2 and DYSTROPHIN. Both the alpha and the beta subtypes of dystroglycan originate via POST-TRANSLATIONAL PROTEIN PROCESSING of a single precursor protein.

Year introduced: 2005(1992)



An order of GRAM-NEGATIVE OXYGENIC PHOTOSYNTHETIC BACTERIA containing CHLOROPHYLL, a and b, but lacking PHYCOBILISOMES (light-harvesting antennae). There are three genera: PROCHLORON; PROCHLOROCOCCUS; and PROCHLOROTHRIX. This order was thought to be the missing link between CYANOBACTERIA and plant CHLOROPLASTS, hence the name.

Year introduced: 2005



A huge subclass of mostly marine CRUSTACEA, containing over 14,000 species. The 10 orders comprise both planktonic and benthic organisms, and include both free-living and parasitic forms. Planktonic copepods form the principle link between PHYTOPLANKTON and the higher trophic levels of the marine food chains.

Year introduced: 2003


SUMO-1 Protein

A 1.5-kDa small ubiquitin-related modifier protein that can covalently bind via an isopeptide link to a number of cellular proteins. It may play a role in intracellular protein transport and a number of other cellular processes.

Year introduced: 2002

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