Glycyrrhizic Acid

A widely used anti-inflammatory agent isolated from the licorice root. It is metabolized to GLYCYRRHETINIC ACID, which inhibits 11-BETA-HYDROXYSTEROID DEHYDROGENASES and other enzymes involved in the metabolism of CORTICOSTEROIDS. Therefore, glycyrrhizic acid, which is the main and sweet component of licorice, has been investigated for its ability to cause hypermineralocorticoidism with sodium retention and potassium loss, edema, increased blood pressure, as well as depression of the renin-angiotensin-aldosterone system.

Year introduced: 1998

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Tree Number(s): D02.455.849.919.530.466

MeSH Unique ID: D019695

Registry Number: 6FO62043WK

Entry Terms:

• Acid, Glycyrrhizic
• Glycyrrhizinic Acid
• Acid, Glycyrrhizinic
• Glycyrrhizin
• Zinc Glycyrrhizate
• Glycyrrhizate, Zinc
• Diammonium Glycyrrhizinate
• Glycyrrhizinate, Diammonium
• Dipotassium Glycyrrhizinate
• Glycyrrhizinate, Dipotassium

Previous Indexing:

• Glycyrrhetinic Acid (1977-1997)
• Glycyrrhiza (1976-1985)

Pharmacologic Action:

• Anti-Inflammatory Agents

All MeSH Categories
Chemicals and Drugs Category
Organic Chemicals
Hydrocarbons
Terpenes
Triterpenes
Pentacyclic Triterpenes
Glycyrrhizic Acid