Tuftsin
N(2)-((1-(N(2)-L-Threonyl)-L-lysyl)-L-prolyl)-L-arginine. A tetrapeptide produced in the spleen by enzymatic cleavage of a leukophilic gamma-globulin. It stimulates the phagocytic activity of blood polymorphonuclear leukocytes and neutrophils in particular. The peptide is located in the Fd fragment of the gamma-globulin molecule.
Year introduced: 1984(1975)
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Subheadings:
Tree Number(s): D12.644.456.840, D12.644.541.500.650.750, D12.776.124.486.485.397.500, D12.776.124.486.485.680.650.750, D12.776.124.790.651.397.500, D12.776.124.790.651.680.650.750, D12.776.377.715.548.397.500, D12.776.377.715.548.680.650.750
MeSH Unique ID: D014405
Registry Number: QF5336J16C
Entry Terms:
- L-Threonyl-L-Lysyl-L-Prolyl-L-Arginine
- Taftsin
- L-Thr-L-Lys-L-Pro-L-Arg
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Pharmacologic Action: