Insulin-Like Growth Factor I

A well-characterized basic peptide believed to be secreted by the liver and to circulate in the blood. It has growth-regulating, insulin-like, and mitogenic activities. This growth factor has a major, but not absolute, dependence on GROWTH HORMONE. It is believed to be mainly active in adults in contrast to INSULIN-LIKE GROWTH FACTOR II, which is a major fetal growth factor.

Year introduced: 1991(1986)

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Tree Number(s): D12.776.124.862.400

MeSH Unique ID: D007334

Registry Number: 67763-96-6

Entry Terms:

• IGF-1
• IGF-I-SmC
• IGF-I
• Insulin-Like Somatomedin Peptide I
• Insulin Like Somatomedin Peptide I
• Somatomedin C
• Insulin Like Growth Factor I

Previous Indexing:

• Growth Substances (1966-1985)
• Insulin (1966-1985)
• Peptides (1966-1985)
• Somatomedins (1973-1985)
• Sulfation Factor (1971-1972)

See Also:

• Receptor, IGF Type 1

All MeSH Categories
Chemicals and Drugs Category
Amino Acids, Peptides, and Proteins
Proteins
Blood Proteins
Somatomedins
Insulin-Like Growth Factor I