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Colistin

Cyclic polypeptide antibiotic from Bacillus colistinus. It is composed of Polymyxins E1 and E2 (or Colistins A, B, and C) which act as detergents on cell membranes. Colistin is less toxic than Polymyxin B, but otherwise similar; the methanesulfonate is used orally.

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Subheadings:

Tree Number(s): D04.345.566.780.110, D10.477.750.110, D12.644.050.600.110, D12.644.066.500.600.110, D12.644.641.780.110, D12.776.543.695.054.600.110

MeSH Unique ID: D003091

Registry Number: Z67X93HJG1

Entry Terms:

  • Colimycin
  • Colisticin
  • Polymyxin E
  • Colistin Sulfate
  • Sulfate, Colistin
  • Totazina
  • Coly-Mycin

Pharmacologic Action:

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