Cerebral Autosomal Recessive Arteriopathy with Subcortical Infarcts and Leukoencephalopathy [Supplementary Concept]

A hereditary autosomal recessive nonhypertensive cerebral small vessel arteriopathy characterized by alopecia, SPONDYLOSIS, and progressive motor dysfunction and DEMENTIA with onset typically in the second or third decade of life. Mutations in the HTRA1 gene have been identified. OMIM: 600142

Date introduced: November 5, 2012

MeSH Unique ID: C563990

Heading Mapped to:

• Alopecia
• Cerebral Infarction
• Spinal Diseases
• Leukoencephalopathies

Entry Terms:

• CARASIL
• Subcortical Vascular Encephalopathy, Progressive
• Cerebrovascular Disease with Thin Skin, Alopecia, and Disc Disease
• Familial Young-Adult-Onset Arteriosclerotic Leukoencephalopathy with Alopecia and Lumbago without Arterial Hypertension
• Nemoto Disease
• MAEDA Syndrome