rhoC GTP-Binding Protein
A rho GTP-binding protein that is prenylated (see PROTEIN PRENYLATION) at its C-terminus and cycles between the cytoplasm and plasma membrane, linking receptor signaling pathways with assembly of FOCAL ADHESIONS; STRESS FIBERS; and contractile ring formation during CYTOKINESIS. It is overexpressed in proliferating and metastatic tumor cells.
Year introduced: 2018
PubMed search builder options
Subheadings:
Tree Number(s): D08.811.277.040.330.300.400.700.650, D12.776.157.325.515.700.650, D12.776.476.338.400.700.650
MeSH Unique ID: D000075024
Registry Number: EC 3.6.5.2
Entry Terms:
- GTP-Binding Protein, rhoC
- rhoC GTP Binding Protein
- rhoC GTPase
- ras Homolog Family Member C
Previous Indexing: