Autophagy-Related Protein 5
An autophagy-related protein that functions in AUTOPHAGOSOME biogenesis. It is conjugated to the ATG12 PROTEIN via a process that is similar to UBIQUITINATION and involves the ATG7 PROTEIN and ATG10 enzyme. The ATG12-ATG5 conjugate acts as an E3 UBIQUITIN LIGASE-like enzyme and is required for the localization of ATG8 PROTEINS to AUTOPHAGOSOME vesicle membranes and modification of membrane lipids.
Year introduced: 2017
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Subheadings:
Tree Number(s): D12.776.094.250
MeSH Unique ID: D000071187
Entry Terms:
- Autophagy Related Protein 5
- Autophagy Protein-5
- Autophagy Protein 5
- Autophagy-Related 5 Protein
- Autophagy Related 5 Protein
- ATG5 Protein
- ATG-5 Protein
- ATG 5 Protein
- Apoptosis-Specific Protein
- Apoptosis Specific Protein
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