Format
Items per page

Send to:

Choose Destination

Links from PubMed

Items: 6

1.

BCHE, fluoride 2

MedGen UID:
865989
Concept ID:
C4017552
Finding
2.

Butyrylcholinesterase deficiency, fluoride 1

MedGen UID:
865987
Concept ID:
C4017550
Finding
3.

Butyrylcholinesterase deficiency, fluoride-resistant, japanese type

MedGen UID:
401238
Concept ID:
C1867469
Disease or Syndrome
4.

Postanesthetic apnea

MedGen UID:
357286
Concept ID:
C1867468
Pathologic Function
5.

Suxamethonium sensitivity

MedGen UID:
351438
Concept ID:
C1622434
Pathologic Function
6.

Deficiency of butyrylcholine esterase

Pseudocholinesterase deficiency is a condition that results in increased sensitivity to certain muscle relaxant drugs used during general anesthesia, called choline esters. These fast-acting drugs, such as succinylcholine and mivacurium, are given to relax the muscles used for movement (skeletal muscles), including the muscles involved in breathing. The drugs are often employed for brief surgical procedures or in emergencies when a breathing tube must be inserted quickly. Normally, these drugs are broken down (metabolized) by the body within a few minutes of being administered, at which time the muscles can move again. However, people with pseudocholinesterase deficiency may not be able to move or breathe on their own for a few hours after the drugs are administered. Affected individuals must be supported with a machine to help them breathe (mechanical ventilation) until the drugs are cleared from the body.People with pseudocholinesterase deficiency may also have increased sensitivity to certain other drugs, including the local anesthetic procaine, and to specific agricultural pesticides. The condition causes no other signs or symptoms and is usually not discovered until an abnormal drug reaction occurs.
[from GHR]

MedGen UID:
220923
Concept ID:
C1283400
Disease or Syndrome
Format
Items per page

Send to:

Choose Destination

Supplemental Content

Find related data

Recent activity

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...
Support Center