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Items: 4

1.

Abdominal obesity metabolic syndrome

MedGen UID:
419670
Concept ID:
C2930930
Disease or Syndrome
2.

ABDOMINAL OBESITY-METABOLIC SYNDROME QUANTITATIVE TRAIT LOCUS 1

MedGen UID:
381359
Concept ID:
C1854178
Disease or Syndrome; Finding
3.

Metabolic syndrome, protection against

MedGen UID:
370158
Concept ID:
C1970051
Disease or Syndrome
4.

Metabolic syndrome X

A clustering of abdominal obesity, high triglycerides, low levels of high density lipoprotein cholesterol (HDLC), high blood pressure, and elevated fasting glucose levels is sometimes called metabolic syndrome X (Reaven, 1988) or abdominal obesity-metabolic syndrome (Bjorntorp, 1991). The syndrome may affect nearly 1 in 4 U.S. adults and is considered a veritable epidemic (Ford et al., 2002). It is a major risk factor for both diabetes mellitus (see 125853 and Haffner et al., 1992) and cardiovascular disease (Isomaa et al., 2001). The etiology is complex, determined by the interplay of both genetic and environmental factors. The prevalence varies substantially among ethnic groups, with the highest rates in Mexican American women (Park et al., 2003). Other factors influencing the metabolic syndrome include age, smoking, alcohol, diet, and physical inactivity. Genetic Heterogeneity of Abdominal Obesity-Metabolic Syndrome AOMS2 (605572) has been mapped to chromosome 17p12. AOMS3 (615812) is caused by mutation in the DYRK1B gene (604556) on chromosome 19q13. [from OMIM]

MedGen UID:
99356
Concept ID:
C0524620
Disease or Syndrome
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