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Items: 17

1.

ajoene

MedGen UID:
26602
Concept ID:
C0051034
Organic Chemical; Pharmacologic Substance
2.

allicin

An allyl-S-compound with the structure C=CCS(=O)SCC=C. [from NCI]

MedGen UID:
25888
Concept ID:
C0051200
Pharmacologic Substance
3.

Nitric Oxide

name of an inorganic chemical [from CHV]

MedGen UID:
14378
Concept ID:
C0028128
Biologically Active Substance; Inorganic Chemical; Pharmacologic Substance
4.

Link brand of magnesium carbonate and aluminum hydroxide

brand of magnesium carbonate and aluminum hydroxide [from CHV]

MedGen UID:
60403
Concept ID:
C0208973
Inorganic Chemical; Pharmacologic Substance
5.

Atherosclerosis

Atherosclerosis is a disease in which plaque builds up inside your arteries. Plaque is a sticky substance made up of fat, cholesterol, calcium, and other substances found in the blood. Over time, plaque hardens and narrows your arteries. That limits the flow of oxygen-rich blood to your body. Atherosclerosis can lead to serious problems, including. -Coronary artery disease. These arteries supply blood to your heart. When they are blocked, you can suffer angina or a heart attack. -Carotid artery disease. These arteries supply blood to your brain. When they are blocked you can suffer a stroke. -Peripheral arterial disease. These arteries are in your arms, legs and pelvis. When they are blocked, you can suffer from numbness, pain and sometimes infections. Atherosclerosis usually doesn't cause symptoms until it severely narrows or totally blocks an artery. Many people don't know they have it until they have a medical emergency. A physical exam, imaging, and other diagnostic tests can tell if you have it. Medicines can slow the progress of plaque buildup. Your doctor may also recommend procedures such as angioplasty to open the arteries, or surgery on the coronary or carotid arteries. Lifestyle changes can also help. These include following a healthy diet, getting regular exercise, maintaining a healthy weight, quitting smoking, and managing stress. . NIH: National Heart, Lung, and Blood Institute.  [from MedlinePlus]

MedGen UID:
13948
Concept ID:
C0004153
Disease or Syndrome
6.

Arginine

One of the twenty common amino acids (building blocks of proteins). Arginine is being studied as a nutritional supplement in the treatment and prevention of cancer and other conditions. [from NCI]

MedGen UID:
13907
Concept ID:
C0003765
Amino Acid, Peptide, or Protein; Biologically Active Substance; Pharmacologic Substance
7.

Citrulline

A non-essential amino acid. In hepatocytes, L-citrulline is synthesized in the urea cycle by the addition of carbon dioxide and ammonia to ornithine. L-citrulline is converted into L-arginine by the enzymes argininosuccinate synthetase and argininosuccinate lyase in the presence of L-aspartate and ATP. Subsequently, L-arginine is converted to nitric oxide by nitric oxide synthase and L-citrulline is regenerated as a by-product . Check for "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=464795&idtype=1" active clinical trials or "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=464795&idtype=1&closed=1" closed clinical trials using this agent. ("http://nciterms.nci.nih.gov:80/NCIBrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C53406" NCI Thesaurus) [from PDQ]

MedGen UID:
983
Concept ID:
C0008864
Amino Acid, Peptide, or Protein; Biologically Active Substance; Pharmacologic Substance
8.

nitrite ion

A nitrogen oxoanion that is formed when nitrous acid is deprotonated. As nitrite is a metabolic end product for nitric oxide (NO), which is increased during inflammation; nitrite levels can be used to assess NO production and thus inflammation. [from NCI]

MedGen UID:
885935
Concept ID:
C3848529
Element, Ion, or Isotope; Pharmacologic Substance
9.

Accumulation

An increase of substance (e.g., proteinaceous fluid and glycogen) in either the intracellular space, extracellular space, or within a hollow organ or structure. [from NCI_CDISC]

MedGen UID:
883922
Concept ID:
C4055506
Finding
10.

Van der Woude syndrome

IRF6-related disorders span a spectrum from isolated cleft lip and palate and Van der Woude syndrome (VWS) at the mild end to popliteal pterygium syndrome (PPS) at the more severe end. Individuals with VWS show one or more of the following anomalies: Congenital, usually bilateral, paramedian lower-lip fistulae (pits) or sometimes small mounds with a sinus tract leading from a mucous gland of the lip. Cleft lip (CL). Cleft palate (CP). Note: Cleft lip with or without cleft palate (CL±P) is observed about twice as often as CP only. Submucous cleft palate (SMCP). The PPS phenotype includes the following: CL±P. Fistulae of the lower lip. Webbing of the skin extending from the ischial tuberosities to the heels. In males: bifid scrotum and cryptorchidism. In females: hypoplasia of the labia majora. Syndactyly of fingers and/or toes. Anomalies of the skin around the nails. A characteristic pyramidal fold of skin overlying the nail of the hallux (almost pathognomonic). In some non-classic forms of PPS: filiform synechiae connecting the upper and lower jaws (syngnathia) or the upper and lower eyelids (ankyloblepharon). In both VWS and PPS, growth and intelligence are normal. [from GeneReviews]

MedGen UID:
61233
Concept ID:
C0175697
Congenital Abnormality; Disease or Syndrome
11.

Plant Preparations

Material prepared from plants. [from MeSH]

MedGen UID:
183699
Concept ID:
C0949854
Pharmacologic Substance
12.

Polysaccharide

A large carbohydrate molecule. It contains many small sugar molecules that are joined chemically. [from NCI]

MedGen UID:
46014
Concept ID:
C0032594
Carbohydrate; Organic Chemical; Pharmacologic Substance
13.

Pharmaceutical Preparations

You may need to take medicines every day, or only once in a while. Either way, you want to make sure that the medicines are safe and will help you get better. In the United States, the Food and Drug Administration is in charge of assuring the safety and effectiveness of both prescription and over-the-counter medicines. Even safe drugs can cause unwanted side effects or interactions with food or other medicines you may be taking. They may not be safe during pregnancy. To reduce the risk of reactions and make sure that you get better, it is important for you to take your medicines correctly and be careful when giving medicines to children.  [from MedlinePlus]

MedGen UID:
8496
Concept ID:
C0013227
Pharmacologic Substance
14.

Electrolyte

substance that while in solution or its pure state will conduct an electric current by means of the movement of ions; in physiology, usually refers to compounds such as sodium, potassium, magnesium and calcium which dissociate fluids into ions that conduct electric currents and that constitute the major force in controlling fluid balance within the body. [from CRISP]

MedGen UID:
3997
Concept ID:
C0013832
Inorganic Chemical; Pharmacologic Substance
15.

Biological Products

Complex pharmaceutical substances, preparations, or agents of organic origin, usually obtained by biological methods or assay. They are used especially in diagnosis and treatment of disease (as vaccines or pollen extracts). Biological products are differentiated from BIOLOGICAL FACTORS in that the latter are compounds with biological or physiological activity made by living organisms. (From Webster's 3d ed) [from MeSH]

MedGen UID:
577
Concept ID:
C0005522
Biologically Active Substance; Pharmacologic Substance
16.

allylthiosulfinate

MedGen UID:
288489
Concept ID:
C1531219
Organic Chemical; Pharmacologic Substance
17.

allimin

MedGen UID:
213339
Concept ID:
C1137587
Pharmacologic Substance
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