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Items: 1 to 20 of 30

1.

Pain

Pain is a feeling triggered in the nervous system. Pain may be sharp or dull. It may come and go, or it may be constant. You may feel pain in one area of your body, such as your back, abdomen or chest or you may feel pain all over, such as when your muscles ache from the flu. Pain can be helpful in diagnosing a problem. Without pain, you might seriously hurt yourself without knowing it, or you might not realize you have a medical problem that needs treatment. Once you take care of the problem, pain usually goes away. However, sometimes pain goes on for weeks, months or even years. This is called chronic pain. Sometimes chronic pain is due to an ongoing cause, such as cancer or arthritis. Sometimes the cause is unknown. Fortunately, there are many ways to treat pain. Treatment varies depending on the cause of pain. Pain relievers, acupuncture and sometimes surgery are helpful.  [from MedlinePlus]

MedGen UID:
45282
Concept ID:
C0030193
Sign or Symptom
2.

Somatostatin

Expressed primarily by human SST Gene (Somatostatin Family) in the hypothalamic median eminence and in pancreatic delta cells, secreted 116-aa 13-kDa (precursor) Somatostatin is an important cyclic tetradecapeptide regulator of endocrine and nervous system function. Somatostatin inhibits release of adenohypophyseal GH, thyrotropin, and corticotropin, pancreatic insulin and glucagon, gastric mucosal gastrin, intestinal mucosal secretin, and renal renin by binding to specific high-affinity cell surface G protein-coupled receptors expressed in a tissue-specific manner. (NCI) [from NCI]

MedGen UID:
11505
Concept ID:
C0037659
Amino Acid, Peptide, or Protein; Hormone; Pharmacologic Substance
3.

Multiple congenital anomalies

Congenital abnormalities that affect more than one organ or body structure. [from MeSH]

MedGen UID:
7806
Concept ID:
C0000772
Congenital Abnormality
4.

Carbachol

A slowly hydrolyzed CHOLINERGIC AGONIST that acts at both MUSCARINIC RECEPTORS and NICOTINIC RECEPTORS. [from MeSH]

MedGen UID:
2817
Concept ID:
C0006945
Organic Chemical; Pharmacologic Substance
5.

Pain

MedGen UID:
880950
Concept ID:
CN236637
Disease or Syndrome
6.

Opioid Receptor Agonist

Any agent that binds to and activates any of the opioid receptor subtypes. Opioid receptor agonists mimic the actions of endogenous opioid peptides. [from NCI]

MedGen UID:
760844
Concept ID:
C3537230
Pharmacologic Substance
7.

Agonist

A drug or substance that binds to a receptor inside a cell or on its surface and causes the same action as the substance that normally binds to the receptor. [from NCI_NCI-GLOSS]

MedGen UID:
459858
Concept ID:
C2987634
Pharmacologic Substance
8.

History of recreational running

The act of traveling on foot at a fast pace. [from NCI]

MedGen UID:
453263
Concept ID:
C2346414
Finding
9.

Impairment

MedGen UID:
151925
Concept ID:
C0684336
Pathologic Function
10.

Severe

Having a high degree of severity. For quantitative traits, a deviation of between four and five standard deviations from the appropriate population mean. [from HPO]

MedGen UID:
104640
Concept ID:
C0205082
Qualitative Concept
11.

Opiate agonist

A class of synthetic chemicals/drugs similar to opiates (opium derivatives) with analgesic properties. Due to binding to opiate receptors, opioids mimic opiate activity on neurons, various cells (i.e. lymphocytes), pain suppression and other neurobehavioral activity. (NCI) [from NCI]

MedGen UID:
66892
Concept ID:
C0242402
Hazardous or Poisonous Substance; Organic Chemical; Pharmacologic Substance
12.

Pertussis

A respiratory infection caused by BORDETELLA PERTUSSIS and characterized by paroxysmal coughing ending in a prolonged crowing intake of breath. [from MeSH]

MedGen UID:
12159
Concept ID:
C0043167
Disease or Syndrome
13.

Somatosensory Disorders

Disorders of sensory information received from superficial and deep regions of the body. The somatosensory system conveys neural impulses which pertain to proprioception, tactile sensation, thermal sensation, pressure sensation, and pain. PERIPHERAL NERVOUS SYSTEM DISEASES; SPINAL CORD DISEASES; and BRAIN DISEASES may be associated with impaired or abnormal somatic sensation. [from MeSH]

MedGen UID:
156044
Concept ID:
C0752262
Disease or Syndrome
14.

Hyperalgesia, Thermal

MedGen UID:
148260
Concept ID:
C0751214
Sign or Symptom
15.

Hyperalgesia, Secondary

MedGen UID:
148258
Concept ID:
C0751212
Sign or Symptom
16.

Hyperalgesia, Primary

MedGen UID:
148257
Concept ID:
C0751211
Sign or Symptom
17.

Abnormality of the nervous system

Structural abnormalities of the central or peripheral nervous system resulting primarily from defects of embryogenesis. [from MeSH]

MedGen UID:
105425
Concept ID:
C0497552
Congenital Abnormality
18.

Allodynia

Pain due to a stimulus that does not normally provoke pain. [from HPO]

MedGen UID:
105350
Concept ID:
C0458247
Finding
19.

Cranioschisis

A congenital abnormality characterized by the failure of the bones of the skull to close. [from NCI]

MedGen UID:
78563
Concept ID:
C0265541
Congenital Abnormality
20.

Clinical finding

clinical manifestations that can be either objective when observed by a physician, or subjective when perceived by the patient. [from CRISP]

MedGen UID:
19974
Concept ID:
C0037088
Sign or Symptom
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