Format

Send to:

Choose Destination

Links from PubMed

Receptor Binding

MedGen UID:
154572
Concept ID:
C0597358
Molecular Function
 

Definition

Receptor Binding involves a temporary non-covalent, typically highly specific and high affinity, interaction through intermolecular physical forces of attraction and spatial complementarity with a diverse group of intrinsic membrane or cytoplasmic proteins that mediate the biological effects of secreted regulatory signaling molecules through modification of the activity of signal transduction pathways. [from NCI]

Recent clinical studies

Etiology

Adu-Gyamfi E, Kim LS, Jardetzky TS, Lamb RA
J Virol 2016 Sep 1;90(17):7778-88. Epub 2016 Aug 12 doi: 10.1128/JVI.00896-16. PMID: 27334593Free PMC Article
Dong J, Sun G, Zhu H
Tumour Biol 2016 Mar;37(3):3257-64. Epub 2015 Oct 5 doi: 10.1007/s13277-015-4174-8. PMID: 26438059
Qian Z, Ou X, Góes LG, Osborne C, Castano A, Holmes KV, Dominguez SR
J Virol 2015 Sep;89(17):8816-27. Epub 2015 Jun 17 doi: 10.1128/JVI.03737-14. PMID: 26085157Free PMC Article
Hooper KA, Crowe JE Jr, Bloom JD
J Virol 2015 Apr;89(7):3737-45. Epub 2015 Jan 21 doi: 10.1128/JVI.00012-15. PMID: 25609803Free PMC Article
Sun X, Cao W, Pappas C, Liu F, Katz JM, Tumpey TM
Virology 2014 Sep;464-465:156-65. Epub 2014 Jul 30 doi: 10.1016/j.virol.2014.07.004. PMID: 25078114

Diagnosis

Dong J, Sun G, Zhu H
Tumour Biol 2016 Mar;37(3):3257-64. Epub 2015 Oct 5 doi: 10.1007/s13277-015-4174-8. PMID: 26438059
Liu Y, Shao XX, Zhang L, Song G, Liu YL, Xu ZG, Guo ZY
Amino Acids 2015 Oct;47(10):2237-43. Epub 2015 May 23 doi: 10.1007/s00726-015-2009-y. PMID: 26002812
Hooper KA, Crowe JE Jr, Bloom JD
J Virol 2015 Apr;89(7):3737-45. Epub 2015 Jan 21 doi: 10.1128/JVI.00012-15. PMID: 25609803Free PMC Article
Watanabe Y, Ito T, Ibrahim MS, Arai Y, Hotta K, Phuong HV, Hang Nle K, Mai le Q, Soda K, Yamaoka M, Poetranto ED, Wulandari L, Hiramatsu H, Daidoji T, Kubota-Koketsu R, Sriwilaijaroen N, Nakaya T, Okuno Y, Takahashi T, Suzuki T, Ito T, Hotta H, Yamashiro T, Hayashi T, Morita K, Ikuta K, Suzuki Y
Biosens Bioelectron 2015 Mar 15;65:211-9. Epub 2014 Oct 22 doi: 10.1016/j.bios.2014.10.036. PMID: 25461160
Zhang L, Song G, Xu T, Wu QP, Shao XX, Liu YL, Xu ZG, Guo ZY
Biochimie 2013 Dec;95(12):2454-9. Epub 2013 Sep 18 doi: 10.1016/j.biochi.2013.09.008. PMID: 24056075

Therapy

Tai W, Wang Y, Fett CA, Zhao G, Li F, Perlman S, Jiang S, Zhou Y, Du L
J Virol 2017 Jan 1;91(1) Epub 2016 Dec 16 doi: 10.1128/JVI.01651-16. PMID: 27795425Free PMC Article
Tang J, Zhang N, Tao X, Zhao G, Guo Y, Tseng CT, Jiang S, Du L, Zhou Y
Hum Vaccin Immunother 2015;11(5):1244-50. doi: 10.1080/21645515.2015.1021527. PMID: 25874632Free PMC Article
Sun X, Cao W, Pappas C, Liu F, Katz JM, Tumpey TM
Virology 2014 Sep;464-465:156-65. Epub 2014 Jul 30 doi: 10.1016/j.virol.2014.07.004. PMID: 25078114
Cho JR, Desai B, Haas MJ, Rollini F, Franchi F, Muñiz-Lozano A, Tello-Montoliu A, Ferrante E, Guzman LA, Bass TA, Angiolillo DJ
J Cardiovasc Transl Res 2014 Feb;7(1):47-52. Epub 2013 Dec 20 doi: 10.1007/s12265-013-9530-8. PMID: 24357254
Wu CS, Wang SC, Gau SS, Tsai HJ, Cheng YC
Biol Psychiatry 2013 Mar 1;73(5):414-21. Epub 2012 Aug 9 doi: 10.1016/j.biopsych.2012.07.006. PMID: 22877922

Prognosis

Leisi R, Di Tommaso C, Kempf C, Ros C
Viruses 2016 Feb 24;8(3):61. doi: 10.3390/v8030061. PMID: 26927158Free PMC Article
Huang JH, Shen ZQ, Lien SP, Hsiao KN, Leng CH, Chen CC, Siu LK, Chong PC
PLoS One 2015;10(8):e0135045. Epub 2015 Aug 13 doi: 10.1371/journal.pone.0135045. PMID: 26271033Free PMC Article
Wu CS, Wang SC, Gau SS, Tsai HJ, Cheng YC
Biol Psychiatry 2013 Mar 1;73(5):414-21. Epub 2012 Aug 9 doi: 10.1016/j.biopsych.2012.07.006. PMID: 22877922
Murray JI, Tonkin ML, Whiting AL, Peng F, Farnell B, Cullen JT, Hof F, Boulanger MJ
BMC Struct Biol 2012 Jul 2;12:16. doi: 10.1186/1472-6807-12-16. PMID: 22747601Free PMC Article
Pang X, Qin S, Zhou HX
Biophys J 2011 Sep 7;101(5):1175-83. doi: 10.1016/j.bpj.2011.06.056. PMID: 21889455Free PMC Article

Clinical prediction guides

Leisi R, Di Tommaso C, Kempf C, Ros C
Viruses 2016 Feb 24;8(3):61. doi: 10.3390/v8030061. PMID: 26927158Free PMC Article
Crusat M, Liu J, Palma AS, Childs RA, Liu Y, Wharton SA, Lin YP, Coombs PJ, Martin SR, Matrosovich M, Chen Z, Stevens DJ, Hien VM, Thanh TT, Nhu le NT, Nguyet LA, Ha do Q, van Doorn HR, Hien TT, Conradt HS, Kiso M, Gamblin SJ, Chai W, Skehel JJ, Hay AJ, Farrar J, de Jong MD, Feizi T
Virology 2013 Dec;447(1-2):326-37. Epub 2013 Sep 17 doi: 10.1016/j.virol.2013.08.010. PMID: 24050651Free PMC Article
Cueno ME, Imai K, Shimizu K, Ochiai K
J Mol Graph Model 2013 Jul;44:161-7. Epub 2013 Jun 13 doi: 10.1016/j.jmgm.2013.05.011. PMID: 23831996
Navalakhe RM, Jagtap DD, Nayak SU, Nandedkar TD, Mahale SD
Chem Biol Drug Des 2013 Aug;82(2):178-88. doi: 10.1111/cbdd.12149. PMID: 23601330
Watanabe T, Shinya K, Watanabe S, Imai M, Hatta M, Li C, Wolter BF, Neumann G, Hanson A, Ozawa M, Yamada S, Imai H, Sakabe S, Takano R, Iwatsuki-Horimoto K, Kiso M, Ito M, Fukuyama S, Kawakami E, Gorai T, Simmons HA, Schenkman D, Brunner K, Capuano SV 3rd, Weinfurter JT, Nishio W, Maniwa Y, Igarashi T, Makino A, Travanty EA, Wang J, Kilander A, Dudman SG, Suresh M, Mason RJ, Hungnes O, Friedrich TC, Kawaoka Y
J Virol 2011 Dec;85(24):13195-203. Epub 2011 Sep 21 doi: 10.1128/JVI.00859-11. PMID: 21937653Free PMC Article

Recent systematic reviews

Islam MA, Bhayye S, Adeniyi AA, Soliman ME, Pillay TS
J Biomol Struct Dyn 2017 Mar;35(4):724-737. Epub 2016 Apr 14 doi: 10.1080/07391102.2016.1160258. PMID: 26950281
Möhl BS, Chen J, Sathiyamoorthy K, Jardetzky TS, Longnecker R
Mol Cells 2016 Apr 30;39(4):286-91. Epub 2016 Apr 6 doi: 10.14348/molcells.2016.0066. PMID: 27094060Free PMC Article
Hanson QM, Barb AW
Biochemistry 2015 May 19;54(19):2931-42. Epub 2015 May 7 doi: 10.1021/acs.biochem.5b00299. PMID: 25926001Free PMC Article
Wally J, Halbrooks PJ, Vonrhein C, Rould MA, Everse SJ, Mason AB, Buchanan SK
J Biol Chem 2006 Aug 25;281(34):24934-44. Epub 2006 Jun 22 doi: 10.1074/jbc.M604592200. PMID: 16793765Free PMC Article
Koussounadis AI, Ritchie DW, Kemp GJ, Secombes CJ
Curr Pharm Des 2004;10(31):3857-71. PMID: 15579075

Supplemental Content

Table of contents

    Recent activity

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...
    Support Center