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Supernumerary nipple

MedGen UID:
505270
Concept ID:
CN002323
Finding
Synonyms: accessory mamilla; accessory mamillas; Accessory nipple; Accessory nipples; POLYMASTIA; POLYTHELIA, FAMILIAL; Supernumerary nipples
Modes of inheritance:
Autosomal dominant inheritance
MedGen UID:
141047
Concept ID:
C0443147
Intellectual Product
Sources: HPO, OMIM, Orphanet
Autosomal dominant inheritance refers to genetic conditions that occur when a mutation is present in one copy of a given gene (i.e., the person is heterozygous).
Autosomal dominant inheritance (HPO, OMIM, Orphanet)
 
OMIM®: 163700

Definition

Presence of more than two nipples. [from HPO]

Clinical features

Abnormality of the thorax
MedGen UID:
867424
Concept ID:
C4021797
Anatomical Abnormality
Any abnormality of the thorax (the region of the body formed by the sternum, the thoracic vertebrae and the ribs).

Recent clinical studies

Etiology

Grimshaw EC, Cohen PR
Dermatol Online J 2013 Jan 15;19(1):4. PMID: 23374946
Rajaratnam K, Kumar PD, Sahasranam KV
Am J Cardiol 2000 Sep 15;86(6):695-7, A9. PMID: 10980229
Schmidt H
Eur J Pediatr 1998 Oct;157(10):821-3. PMID: 9809822
Urbani CE, Betti R
Int J Dermatol 1996 May;35(5):349-52. PMID: 8734657
Halal F, Setton N, Wang NS
Am J Med Genet 1991 Mar 15;38(4):552-6. doi: 10.1002/ajmg.1320380411. PMID: 2063897

Diagnosis

Yilmaz AE, Sarifakioglu E, Dogan G, Cakir B, Karabel M, Gorpelioglu C, Turkay S
Pediatr Int 2010 Aug;52(4):e190-1. doi: 10.1111/j.1442-200X.2010.03120.x. PMID: 20958861
Manglik N, Berlingeri-Ramos AC, Boroumand N, Eltorky M
J Cutan Pathol 2010 Nov;37(11):1178-81. doi: 10.1111/j.1600-0560.2009.01397.x. PMID: 19694882
Kanitakis J
J Cutan Pathol 2010 Jul;37(7):797-801. Epub 2009 Jul 15 doi: 10.1111/j.1600-0560.2009.01373.x. PMID: 19614734
Mak CT, Veras E, Loveless MB
J Pediatr Adolesc Gynecol 2009 Aug;22(4):e41-4. Epub 2009 Jun 2 doi: 10.1016/j.jpag.2008.03.001. PMID: 19493516
Cabo H, Stolz W
Dermatol Surg 2004 Jul;30(7):1068-9. doi: 10.1111/j.1524-4725.2004.30319.x. PMID: 15209804

Prognosis

Rosa RF, Zen PR, Graziadio C, Paskulin GA
Arq Bras Cardiol 2009 Feb;92(2):e6-8, e33-5. PMID: 19360235
Rajaratnam K, Kumar PD, Sahasranam KV
Am J Cardiol 2000 Sep 15;86(6):695-7, A9. PMID: 10980229

Clinical prediction guides

Mehes K
Cancer Genet Cytogenet 1996 Feb;86(2):129-30. PMID: 8603338
Berman MA, Davis GD
J Reprod Med 1994 Aug;39(8):657-9. PMID: 7996535
Lurie IW, Wulfsberg EA
Genet Couns 1994;5(3):275-81. PMID: 7811428
Mehregan AH
J Cutan Pathol 1981 Apr;8(2):96-104. PMID: 7276291

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