Format

Send to:

Choose Destination

Links from PubMed

Multiple organ failure

MedGen UID:
6462
Concept ID:
C0026766
Pathologic Function
Synonyms: Failure, Multiple Organ; MODS; Multiple Organ Dysfunction Syndrome; Multiple Organ Failure; Multiple Organ Failures; Organ Dysfunction Syndrome, Multiple; Organ Failure, Multiple
SNOMED CT: Multisystem organ failure (57653000); Multiple systems organ failure (57653000); MOF - Multiple organ failure (57653000); Multi-organ failure (57653000); MOSF - Multiple organ systems failure (57653000); Multiple organ systems failure (57653000); MSOF - Multiple systems organ failure (57653000); Multiple organ dysfunction syndrome (238148004); MODS - Multiple organ dysfunction syndrome (238148004); Multiple organ failure (57653000)
 

Definition

A progressive condition usually characterized by combined failure of several organs such as the lungs, liver, kidney, along with some clotting mechanisms, usually postinjury or postoperative. [from MeSH]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVMultiple organ failure

Recent clinical studies

Etiology

Fröhlich M, Wafaisade A, Mansuri A, Koenen P, Probst C, Maegele M, Bouillon B, Sakka SG
Scand J Trauma Resusc Emerg Med 2016 Nov 3;24(1):130. doi: 10.1186/s13049-016-0321-5. PMID: 27809885Free PMC Article
Rodríguez-Villar S, Fernández-Méndez R, Adams G, Rodríguez-García JL, Arévalo-Serrano J, Sánchez-Casado M, Kilgour PM
J Crit Care 2015 Jun;30(3):511-7. Epub 2015 Feb 26 doi: 10.1016/j.jcrc.2015.02.006. PMID: 25817326
Sevketoglu E, Yildizdas D, Horoz OO, Kihtir HS, Kendirli T, Bayraktar S, Carcillo JA
Pediatr Crit Care Med 2014 Oct;15(8):e354-9. doi: 10.1097/PCC.0000000000000227. PMID: 25068251Free PMC Article
Sauaia A, Moore EE, Johnson JL, Chin TL, Banerjee A, Sperry JL, Maier RV, Burlew CC
J Trauma Acute Care Surg 2014 Mar;76(3):582-92, discussion 592-3. doi: 10.1097/TA.0000000000000147. PMID: 24553523Free PMC Article
Harr JN, Moore EE, Johnson J, Chin TL, Wohlauer MV, Maier R, Cuschieri J, Sperry J, Banerjee A, Silliman CC, Sauaia A
Crit Care Med 2013 Feb;41(2):399-404. doi: 10.1097/CCM.0b013e31826ab38b. PMID: 23263579Free PMC Article

Diagnosis

Fröhlich M, Wafaisade A, Mansuri A, Koenen P, Probst C, Maegele M, Bouillon B, Sakka SG
Scand J Trauma Resusc Emerg Med 2016 Nov 3;24(1):130. doi: 10.1186/s13049-016-0321-5. PMID: 27809885Free PMC Article
Bechtel-Grosch U, Beguelin C, Berezowska S, Dufour JF, Takala J, Schefold JC
J Med Case Rep 2016 Jan 20;10:7. doi: 10.1186/s13256-015-0777-3. PMID: 26785992Free PMC Article
Dewar DC, White A, Attia J, Tarrant SM, King KL, Balogh ZJ
J Trauma Acute Care Surg 2014 Oct;77(4):624-9. doi: 10.1097/TA.0000000000000406. PMID: 25250605
Sevketoglu E, Yildizdas D, Horoz OO, Kihtir HS, Kendirli T, Bayraktar S, Carcillo JA
Pediatr Crit Care Med 2014 Oct;15(8):e354-9. doi: 10.1097/PCC.0000000000000227. PMID: 25068251Free PMC Article
Sauaia A, Moore EE, Johnson JL, Chin TL, Banerjee A, Sperry JL, Maier RV, Burlew CC
J Trauma Acute Care Surg 2014 Mar;76(3):582-92, discussion 592-3. doi: 10.1097/TA.0000000000000147. PMID: 24553523Free PMC Article

Therapy

Nakashima K, Aoshima M, Suzuki F, Watanabe J, Otsuka Y
Intern Med 2016;55(5):527-31. Epub 2016 Mar 1 doi: 10.2169/internalmedicine.55.4857. PMID: 26935377
Bechtel-Grosch U, Beguelin C, Berezowska S, Dufour JF, Takala J, Schefold JC
J Med Case Rep 2016 Jan 20;10:7. doi: 10.1186/s13256-015-0777-3. PMID: 26785992Free PMC Article
Sevketoglu E, Yildizdas D, Horoz OO, Kihtir HS, Kendirli T, Bayraktar S, Carcillo JA
Pediatr Crit Care Med 2014 Oct;15(8):e354-9. doi: 10.1097/PCC.0000000000000227. PMID: 25068251Free PMC Article
Ödek Ç, Kendirli T, Yaman A, Ileri T, Kuloğlu Z, Ince E
J Pediatr Hematol Oncol 2014 Mar;36(2):e88-90. doi: 10.1097/MPH.0b013e31828e505b. PMID: 23619107
Harr JN, Moore EE, Johnson J, Chin TL, Wohlauer MV, Maier R, Cuschieri J, Sperry J, Banerjee A, Silliman CC, Sauaia A
Crit Care Med 2013 Feb;41(2):399-404. doi: 10.1097/CCM.0b013e31826ab38b. PMID: 23263579Free PMC Article

Prognosis

Hutchings L, Watkinson P, Young JD, Willett K
J Trauma Acute Care Surg 2017 Mar;82(3):534-541. doi: 10.1097/TA.0000000000001328. PMID: 28030507Free PMC Article
Fröhlich M, Wafaisade A, Mansuri A, Koenen P, Probst C, Maegele M, Bouillon B, Sakka SG
Scand J Trauma Resusc Emerg Med 2016 Nov 3;24(1):130. doi: 10.1186/s13049-016-0321-5. PMID: 27809885Free PMC Article
Rodríguez-Villar S, Fernández-Méndez R, Adams G, Rodríguez-García JL, Arévalo-Serrano J, Sánchez-Casado M, Kilgour PM
J Crit Care 2015 Jun;30(3):511-7. Epub 2015 Feb 26 doi: 10.1016/j.jcrc.2015.02.006. PMID: 25817326
Dewar DC, White A, Attia J, Tarrant SM, King KL, Balogh ZJ
J Trauma Acute Care Surg 2014 Oct;77(4):624-9. doi: 10.1097/TA.0000000000000406. PMID: 25250605
Sevketoglu E, Yildizdas D, Horoz OO, Kihtir HS, Kendirli T, Bayraktar S, Carcillo JA
Pediatr Crit Care Med 2014 Oct;15(8):e354-9. doi: 10.1097/PCC.0000000000000227. PMID: 25068251Free PMC Article

Clinical prediction guides

Fröhlich M, Wafaisade A, Mansuri A, Koenen P, Probst C, Maegele M, Bouillon B, Sakka SG
Scand J Trauma Resusc Emerg Med 2016 Nov 3;24(1):130. doi: 10.1186/s13049-016-0321-5. PMID: 27809885Free PMC Article
Bechtel-Grosch U, Beguelin C, Berezowska S, Dufour JF, Takala J, Schefold JC
J Med Case Rep 2016 Jan 20;10:7. doi: 10.1186/s13256-015-0777-3. PMID: 26785992Free PMC Article
Dewar DC, White A, Attia J, Tarrant SM, King KL, Balogh ZJ
J Trauma Acute Care Surg 2014 Oct;77(4):624-9. doi: 10.1097/TA.0000000000000406. PMID: 25250605
Sevketoglu E, Yildizdas D, Horoz OO, Kihtir HS, Kendirli T, Bayraktar S, Carcillo JA
Pediatr Crit Care Med 2014 Oct;15(8):e354-9. doi: 10.1097/PCC.0000000000000227. PMID: 25068251Free PMC Article
Sauaia A, Moore EE, Johnson JL, Chin TL, Banerjee A, Sperry JL, Maier RV, Burlew CC
J Trauma Acute Care Surg 2014 Mar;76(3):582-92, discussion 592-3. doi: 10.1097/TA.0000000000000147. PMID: 24553523Free PMC Article

Recent systematic reviews

Boyd JH, Fjell CD, Russell JA, Sirounis D, Cirstea MS, Walley KR
J Innate Immun 2016;8(2):211-20. Epub 2016 Jan 13 doi: 10.1159/000442976. PMID: 26756586
Rosenthal MD, Moore FA
Surg Infect (Larchmt) 2016 Apr;17(2):167-72. Epub 2015 Dec 21 doi: 10.1089/sur.2015.184. PMID: 26689501Free PMC Article
Easton R, Balogh ZJ
Injury 2014 Jun;45(6):934-41. Epub 2013 Dec 8 doi: 10.1016/j.injury.2013.12.002. PMID: 24388280
O'Brien JM Jr, Ali NA, Abraham E
Crit Care 2008;12(5):228. Epub 2008 Oct 14 doi: 10.1186/cc6950. PMID: 18983708Free PMC Article
Simkova V, Baumgart K, Radermacher P, Barth E, Calzia E
Crit Care 2007;11(4):221. doi: 10.1186/cc5938. PMID: 17764584Free PMC Article

Supplemental Content

Table of contents

    Medical Encyclopedia

    Diseases & Conditions:

    Recent activity

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...
    Support Center