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Items: 4

1.

(R)-isomer; corydalis B of tetrahydropalmatine

MedGen UID:
212368
Concept ID:
C0896862
Organic Chemical; Pharmacologic Substance
2.

Warfarin

A drug that prevents blood from clotting. It belongs to the family of drugs called anticoagulants (blood thinners). [from NCI_NCI-GLOSS]

MedGen UID:
22695
Concept ID:
C0043031
Hazardous or Poisonous Substance; Organic Chemical; Pharmacologic Substance
3.

miglitol

A desoxynojirimycin derivative and inhibitor of alpha-glucosidase with antihyperglycemic activity. Miglitol binds to and inhibits alpha-glucosidase, an enteric enzyme found in the brush border of the small intestines that hydrolyzes oligosaccharides and disaccharides into glucose and other monosaccharides. This prevents the breakdown of larger carbohydrates into glucose and decreases the rise in postprandial blood glucose levels. Compared to acarbose, miglitol is systemically absorbed. [from NCI]

MedGen UID:
17659
Concept ID:
C0066535
Organic Chemical; Pharmacologic Substance
4.

Warfarin sodium

The sodium salt form of warfarin, a coumarin and a vitamin K antagonist, with anticoagulant activity. Warfarin sodium inhibits both vitamin K and vitamin K epoxide reductases, thereby interfering with the cyclic interconversion of vitamin K epoxide to its reduced form, vitamin KH2. Vitamin KH2 is a cofactor for the carboxylation of glutamate residues on the N-terminal regions of vitamin K-dependent proteins. As a result, maturation of vitamin K-dependent coagulation factors II, VII, IX, and X and anticoagulant proteins C and S is inhibited. Without these coagulation factors, thrombogenesis and blood clot formation are prevented. [from NCI]

MedGen UID:
87667
Concept ID:
C0376218
Hazardous or Poisonous Substance; Organic Chemical; Pharmacologic Substance
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