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Dementia

MedGen UID:
504574
Concept ID:
CN000683
Finding
Synonyms: Progressive dementia
 

Definition

A loss of global cognitive ability of sufficient amount to interfere with normal social or occupational function. Dementia represents a loss of previously present cognitive abilities, generally in adults, and can affect memory, thinking, language, judgment, and behavior. [from HPO]

Professional guidelines

PubMed

Moore A, Patterson C, Lee L, Vedel I, Bergman H; Canadian Consensus Conference on the Diagnosis and Treatment of Dementia.
Can Fam Physician 2014 May;60(5):433-8. PMID: 24829003Free PMC Article

Recent clinical studies

Etiology

Moon Y, Lee H, Namgung OK, Han SH
J Korean Med Sci 2016 Oct;31(10):1635-40. doi: 10.3346/jkms.2016.31.10.1635. PMID: 27550494Free PMC Article
Wiersma EC, O'Connor DL, Loiselle L, Hickman K, Heibein B, Hounam B, Mann J
Dementia (London) 2016 May;15(3):414-33. doi: 10.1177/1471301216642339. PMID: 27170590
Batra S, Sullivan J, Williams BR, Geldmacher DS
Dementia (London) 2016 Sep;15(5):1260-78. Epub 2015 Oct 22 doi: 10.1177/1471301215601619. PMID: 26493236
Innes A, Page SJ, Cutler C
Dementia (London) 2016 Nov;15(6):1643-1665. Epub 2015 Feb 10 doi: 10.1177/1471301215570346. PMID: 25673650
Carone L, Tischler V, Dening T
Dementia (London) 2016 Nov;15(6):1358-1376. Epub 2014 Nov 26 doi: 10.1177/1471301214560239. PMID: 25427788

Diagnosis

Wiersma EC, O'Connor DL, Loiselle L, Hickman K, Heibein B, Hounam B, Mann J
Dementia (London) 2016 May;15(3):414-33. doi: 10.1177/1471301216642339. PMID: 27170590
Snow K, Cheston R, Smart C
Dementia (London) 2016 Nov;15(6):1515-1533. Epub 2015 Feb 18 doi: 10.1177/1471301214564447. PMID: 25697501
Dodd E, Cheston R, Cullum S, Jefferies R, Ismail S, Gatting L, Fear T, Gray R
Dementia (London) 2016 Nov;15(6):1586-1604. Epub 2015 Jan 22 doi: 10.1177/1471301214566476. PMID: 25613981
Westwood S
Dementia (London) 2016 Nov;15(6):1494-1514. Epub 2014 Dec 19 doi: 10.1177/1471301214564446. PMID: 25527570
Sullivan KA, Beattie E, Khawaja NG, Wilz G, Cunningham L
Dementia (London) 2016 Nov;15(6):1474-1493. Epub 2014 Oct 2 doi: 10.1177/1471301214553038. PMID: 25280493

Therapy

Quasdorf T, Riesner C, Dichter MN, Dortmann O, Bartholomeyczik S, Halek M
J Clin Nurs 2017 Mar;26(5-6):751-765. Epub 2016 Dec 7 doi: 10.1111/jocn.13522. PMID: 27534732
Lo MH, Lin CL, Chuang E, Chuang TY, Kao CH
Acta Neurol Scand 2017 Feb;135(2):197-203. Epub 2016 Mar 1 doi: 10.1111/ane.12581. PMID: 26932875
Manabe Y, Ino T, Yamanaka K, Kosaka K
Psychogeriatrics 2016 May;16(3):202-8. Epub 2015 Jul 16 doi: 10.1111/psyg.12140. PMID: 26179411
Algar K, Woods RT, Windle G
Dementia (London) 2016 Jul;15(4):832-57. Epub 2014 Jun 24 doi: 10.1177/1471301214540163. PMID: 24961999
Turró-Garriga O, Calvó-Perxas L, Albaladejo R, Alsina E, Cuy JM, Llinàs-Reglà J, Roig AM, Serena J, Vallmajó N, Viñas M, López-Pousa S, Vilalta-Franch J, Garre-Olmo J; Registry of Dementia of Girona Study Group (ReDeGi Study Group).
Arch Gerontol Geriatr 2015 May-Jun;60(3):448-52. Epub 2015 Feb 7 doi: 10.1016/j.archger.2015.01.020. PMID: 25716011

Prognosis

Buschke H, Mowrey WB, Ramratan WS, Zimmerman ME, Loewenstein DA, Katz MJ, Lipton RB
Arch Clin Neuropsychol 2017 Feb;32(1):29-39. Epub 2016 Sep 27 doi: 10.1093/arclin/acw083. PMID: 27680087
Lo MH, Lin CL, Chuang E, Chuang TY, Kao CH
Acta Neurol Scand 2017 Feb;135(2):197-203. Epub 2016 Mar 1 doi: 10.1111/ane.12581. PMID: 26932875
Brodaty H, Woolf C, Andersen S, Barzilai N, Brayne C, Cheung KS, Corrada MM, Crawford JD, Daly C, Gondo Y, Hagberg B, Hirose N, Holstege H, Kawas C, Kaye J, Kochan NA, Lau BH, Lucca U, Marcon G, Martin P, Poon LW, Richmond R, Robine JM, Skoog I, Slavin MJ, Szewieczek J, Tettamanti M, Viña J, Perls T, Sachdev PS
BMC Neurol 2016 Apr 21;16:52. doi: 10.1186/s12883-016-0569-4. PMID: 27098177Free PMC Article
Kochan NA, Bunce D, Pont S, Crawford JD, Brodaty H, Sachdev PS
Am J Geriatr Psychiatry 2016 Mar;24(3):221-31. Epub 2015 Dec 22 doi: 10.1016/j.jagp.2015.12.005. PMID: 26905045
Pase MP, Beiser A, Aparicio H, DeCarli C, Vasan RS, Murabito J, Seshadri S
Alzheimers Dement 2016 Apr;12(4):438-45. Epub 2015 Nov 2 doi: 10.1016/j.jalz.2015.09.006. PMID: 26542262Free PMC Article

Clinical prediction guides

Buschke H, Mowrey WB, Ramratan WS, Zimmerman ME, Loewenstein DA, Katz MJ, Lipton RB
Arch Clin Neuropsychol 2017 Feb;32(1):29-39. Epub 2016 Sep 27 doi: 10.1093/arclin/acw083. PMID: 27680087
Manabe Y, Ino T, Yamanaka K, Kosaka K
Psychogeriatrics 2016 May;16(3):202-8. Epub 2015 Jul 16 doi: 10.1111/psyg.12140. PMID: 26179411
Sullivan KA, Beattie E, Khawaja NG, Wilz G, Cunningham L
Dementia (London) 2016 Nov;15(6):1474-1493. Epub 2014 Oct 2 doi: 10.1177/1471301214553038. PMID: 25280493
Algar K, Woods RT, Windle G
Dementia (London) 2016 Jul;15(4):832-57. Epub 2014 Jun 24 doi: 10.1177/1471301214540163. PMID: 24961999
Regan JL
Dementia (London) 2016 Jul;15(4):702-20. Epub 2014 May 22 doi: 10.1177/1471301214534423. PMID: 24858552

Recent systematic reviews

Goodarzi Z, Mele B, Guo S, Hanson H, Jette N, Patten S, Pringsheim T, Holroyd-Leduc J
BMC Neurol 2016 Nov 25;16(1):244. doi: 10.1186/s12883-016-0754-5. PMID: 27887589Free PMC Article
Harrison JK, Stott DJ, McShane R, Noel-Storr AH, Swann-Price RS, Quinn TJ
Cochrane Database Syst Rev 2016 Nov 21;11:CD011333. doi: 10.1002/14651858.CD011333.pub2. PMID: 27869298
Mitchell JI, Long JC, Braithwaite J, Brodaty H
J Am Med Dir Assoc 2016 Feb;17(2):183.e17-27. Epub 2016 Jan 6 doi: 10.1016/j.jamda.2015.11.015. PMID: 26778490
Mitchell G, McCormack B, McCance T
Dementia (London) 2016 Sep;15(5):976-1001. Epub 2014 Aug 25 doi: 10.1177/1471301214548522. PMID: 25160532
Algar K, Woods RT, Windle G
Dementia (London) 2016 Jul;15(4):832-57. Epub 2014 Jun 24 doi: 10.1177/1471301214540163. PMID: 24961999

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