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Adverse Event

MedGen UID:
209094
Concept ID:
C0877248
Pathologic Function
Synonyms: Adverse Experience; AE
 

Definition

Any unfavorable or unintended disease, sign, or symptom (including an abnormal laboratory finding) that is temporally associated with the use of a medical treatment or procedure, and that may or may not be considered related to the medical treatment or procedure. Such events can be related to the intervention, dose, route of administration, patient, or caused by an interaction with another drug(s) or procedure(s). [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAdverse Event

Recent clinical studies

Etiology

King A, Bottle A, Faiz O, Aylin P
Ann Surg 2017 May;265(5):910-915. doi: 10.1097/SLA.0000000000001792. PMID: 27192350
Leroux TS, Basques BA, Frank RM, Griffin JW, Nicholson GP, Cole BJ, Romeo AA, Verma NN
J Shoulder Elbow Surg 2016 Nov;25(11):1780-1786. Epub 2016 Jun 6 doi: 10.1016/j.jse.2016.04.006. PMID: 27282739
Shimabukuro TT, Nguyen M, Martin D, DeStefano F
Vaccine 2015 Aug 26;33(36):4398-405. Epub 2015 Jul 22 doi: 10.1016/j.vaccine.2015.07.035. PMID: 26209838Free PMC Article
McDonald CJ, Kalisch Ellett LM, Barratt JD, Caughey GE
Drug Saf 2014 Dec;37(12):1029-35. doi: 10.1007/s40264-014-0235-y. PMID: 25361529
Stockwell DC, Kirkendall E, Muething SE, Kloppenborg E, Vinodrao H, Jacobs BR
J Patient Saf 2013 Dec;9(4):203-10. doi: 10.1097/PTS.0000000000000055. PMID: 24257063

Diagnosis

King A, Bottle A, Faiz O, Aylin P
Ann Surg 2017 May;265(5):910-915. doi: 10.1097/SLA.0000000000001792. PMID: 27192350
Kurutkan MN, Usta E, Orhan F, Simsekler MC
Int J Risk Saf Med 2015;27(1):11-21. doi: 10.3233/JRS-150639. PMID: 25766063
Marquet K, Claes N, De Troy E, Kox G, Droogmans M, Schrooten W, Weekers F, Vlayen A, Vandersteen M, Vleugels A
Crit Care Med 2015 May;43(5):1053-61. doi: 10.1097/CCM.0000000000000932. PMID: 25756416Free PMC Article
Forster AJ, Taljaard M, Bennett C, van Walraven C
PLoS One 2012;7(7):e41239. Epub 2012 Jul 26 doi: 10.1371/journal.pone.0041239. PMID: 22844445Free PMC Article
Dickerman MJ, Jacobs BR, Vinodrao H, Stockwell DC
Pediatrics 2011 Apr;127(4):e1035-41. Epub 2011 Mar 14 doi: 10.1542/peds.2009-3432. PMID: 21402631

Therapy

King A, Bottle A, Faiz O, Aylin P
Ann Surg 2017 May;265(5):910-915. doi: 10.1097/SLA.0000000000001792. PMID: 27192350
Zhong X, Lim EA, Hershman DL, Moinpour CM, Unger J, Lee SM
J Oncol Pract 2016 Mar;12(3):e270-80, 245-6. Epub 2016 Feb 23 doi: 10.1200/JOP.2015.006106. PMID: 26907453
Shimabukuro TT, Nguyen M, Martin D, DeStefano F
Vaccine 2015 Aug 26;33(36):4398-405. Epub 2015 Jul 22 doi: 10.1016/j.vaccine.2015.07.035. PMID: 26209838Free PMC Article
McDonald CJ, Kalisch Ellett LM, Barratt JD, Caughey GE
Pharmacoepidemiol Drug Saf 2015 Apr;24(4):399-405. Epub 2014 May 20 doi: 10.1002/pds.3648. PMID: 24841749
McDonald CJ, Kalisch Ellett LM, Barratt JD, Caughey GE
Drug Saf 2014 Dec;37(12):1029-35. doi: 10.1007/s40264-014-0235-y. PMID: 25361529

Prognosis

Thanarajasingam G, Atherton PJ, Novotny PJ, Loprinzi CL, Sloan JA, Grothey A
Lancet Oncol 2016 May;17(5):663-70. Epub 2016 Apr 12 doi: 10.1016/S1470-2045(16)00038-3. PMID: 27083333Free PMC Article
Stockwell DC, Kirkendall E, Muething SE, Kloppenborg E, Vinodrao H, Jacobs BR
J Patient Saf 2013 Dec;9(4):203-10. doi: 10.1097/PTS.0000000000000055. PMID: 24257063
Heard GC, Sanderson PM, Thomas RD
Anesth Analg 2012 Mar;114(3):604-14. Epub 2011 Aug 4 doi: 10.1213/ANE.0b013e31822649e8. PMID: 21821515
Dickerman MJ, Jacobs BR, Vinodrao H, Stockwell DC
Pediatrics 2011 Apr;127(4):e1035-41. Epub 2011 Mar 14 doi: 10.1542/peds.2009-3432. PMID: 21402631
Kim MH, Lin J, Hussein M, Battleman D
Curr Med Res Opin 2009 Dec;25(12):3037-47. doi: 10.1185/03007990903368716. PMID: 19852699

Clinical prediction guides

Park T, Hadsall RS, Schommer JC, Gross CR, Rector TS, Davison ML
Res Social Adm Pharm 2015 Sep-Oct;11(5):651-63. Epub 2014 Dec 18 doi: 10.1016/j.sapharm.2014.11.005. PMID: 25592190
Darssan D, Thompson MH, Pettitt AN
Stat Med 2014 Mar 30;33(7):1146-61. Epub 2013 Oct 7 doi: 10.1002/sim.6011. PMID: 24122859
Stockwell DC, Kirkendall E, Muething SE, Kloppenborg E, Vinodrao H, Jacobs BR
J Patient Saf 2013 Dec;9(4):203-10. doi: 10.1097/PTS.0000000000000055. PMID: 24257063
Forster AJ, Taljaard M, Bennett C, van Walraven C
PLoS One 2012;7(7):e41239. Epub 2012 Jul 26 doi: 10.1371/journal.pone.0041239. PMID: 22844445Free PMC Article
Dickerman MJ, Jacobs BR, Vinodrao H, Stockwell DC
Pediatrics 2011 Apr;127(4):e1035-41. Epub 2011 Mar 14 doi: 10.1542/peds.2009-3432. PMID: 21402631

Recent systematic reviews

Flaig T, Douros A, Bronder E, Klimpel A, Kreutz R, Garbe E
J Clin Pharm Ther 2016 Dec;41(6):718-721. Epub 2016 Sep 27 doi: 10.1111/jcpt.12456. PMID: 27670839
Chen TW, Razak AR, Bedard PL, Siu LL, Hansen AR
Ann Oncol 2015 Sep;26(9):1824-9. Epub 2015 Apr 17 doi: 10.1093/annonc/mdv182. PMID: 25888611
Clarkson CE, O'mahony D, Jones DE
Acta Obstet Gynecol Scand 2015 May;94(5):453-64. Epub 2015 Mar 3 doi: 10.1111/aogs.12587. PMID: 25603694
Courtot M, Brinkman RR, Ruttenberg A
PLoS One 2014;9(3):e92632. Epub 2014 Mar 25 doi: 10.1371/journal.pone.0092632. PMID: 24667848Free PMC Article
Watanabe N, Omori IM, Nakagawa A, Cipriani A, Barbui C, McGuire H, Churchill R, Furukawa TA; MANGA (Meta-Analysis of New Generation Antidepressants) Study Group.
CNS Drugs 2010 Jan;24(1):35-53. doi: 10.2165/11319480-000000000-00000. PMID: 20030418

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