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Items: 13

1.

Antibodies, Bispecific

Antibodies, often monoclonal, in which the two antigen-binding sites are specific for separate ANTIGENIC DETERMINANTS. They are artificial antibodies produced by chemical crosslinking, fusion of HYBRIDOMA cells, or by molecular genetic techniques. They function as the main mediators of targeted cellular cytotoxicity and have been shown to be efficient in the targeting of drugs, toxins, radiolabeled haptens, and effector cells to diseased tissue, primarily tumors. [from MeSH]

MedGen UID:
60158
Concept ID:
C0206492
Amino Acid, Peptide, or Protein; Immunologic Factor; Pharmacologic Substance
2.

Dissociation - mental defense mechanism

Used generally to describe the process whereby thoughts, attitudes, emotions, or a coordinated set of activities becomes separated from one's personality or mental processes. Compare DISSOCIATIVE DISORDERS. [from PSY]

MedGen UID:
88527
Concept ID:
C0086168
Mental or Behavioral Dysfunction
3.

Egg lysozyme

MedGen UID:
873851
Concept ID:
C4040986
Amino Acid, Peptide, or Protein; Enzyme; Pharmacologic Substance
4.

Improved

Condition changed and/or recovered [from CCC]

MedGen UID:
512204
Concept ID:
C0184511
Finding
5.

antigen binding

Antigen Binding Interaction involves specific and high affinity non-covalent interaction (binding) of an endogenous antibody through intermolecular physical forces of attraction and spatial complementarity with a soluble or particulate substance (antigen) that induces an immune response. [from NCI]

MedGen UID:
257852
Concept ID:
C1148575
Molecular Function
6.

Lysozyme

A lysozyme (muramidase) test system is a device intended to measure the activity of the bacteriolytic enzyme lysozyme (muramidase) in serum, plasma, leukocytes, and urine. Lysozyme measurements are used in the diagnosis and treatment of monocytic leukemia and kidney disease. [from SPN]

MedGen UID:
6466
Concept ID:
C0026794
Amino Acid, Peptide, or Protein; Enzyme; Pharmacologic Substance
7.

Endoglycosidases

MedGen UID:
760845
Concept ID:
C3537242
Amino Acid, Peptide, or Protein; Enzyme; Pharmacologic Substance
8.

Leftose

MedGen UID:
44088
Concept ID:
C0023215
Amino Acid, Peptide, or Protein; Enzyme; Pharmacologic Substance
9.

Oxazolone

Immunologic adjuvant and sensitizing agent. [from MeSH]

MedGen UID:
18240
Concept ID:
C0030005
Organic Chemical; Pharmacologic Substance
10.

Glycosidase

covering the sugar hydrolases. [from CRISP]

MedGen UID:
5349
Concept ID:
C0017976
Amino Acid, Peptide, or Protein; Enzyme; Pharmacologic Substance
11.

Antibody Specificity

The property of antibodies which enables them to react with some ANTIGENIC DETERMINANTS and not with others. Specificity is dependent on chemical composition, physical forces, and molecular structure at the binding site. [from MeSH]

MedGen UID:
1586
Concept ID:
C0003264
Molecular Function
12.

Antibody Affinity

A measure of the binding strength between antibody and a simple hapten or antigen determinant. It depends on the closeness of stereochemical fit between antibody combining sites and antigen determinants, on the size of the area of contact between them, and on the distribution of charged and hydrophobic groups. It includes the concept of "avidity," which refers to the strength of the antigen-antibody bond after formation of reversible complexes. [from MeSH]

MedGen UID:
1582
Concept ID:
C0003255
Molecular Function
13.

Humoral immune reaction

The processes triggered by interactions of ANTIBODIES with their ANTIGENS. [from MeSH]

MedGen UID:
337
Concept ID:
C0003314
Molecular Function
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