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Items: 2

1.

Reduced factor XII activity

Decreased activity of coagulation factor XII. Factor XII (fXII) is part of the intrinsic coagulation pathway and binds to exposed collagen at site of vessel wall injury, activated by high-MW kininogen and kallikrein, thereby initiating the coagulation cascade. [from HPO]

MedGen UID:
505700
Concept ID:
CN004286
Finding
2.

Factor XII deficiency disease

An absence or reduced level of blood coagulation factor XII. It normally occurs in the absence of patient or family history of hemorrhagic disorders and is marked by prolonged clotting time. [from MeSH]

MedGen UID:
8772
Concept ID:
C0015526
Disease or Syndrome

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