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Items: 6

1.

Zollinger-Ellison syndrome

A condition in which there is increased production of gastrin by a gastrin-secreting tumor (usually located in the pancreas, duodenum, or abdominal lymph nodes) that stimulates the gastric mucosa to maximal activity, with consequent gastrointestinal mucosal ulceration. [from HPO]

MedGen UID:
53129
Concept ID:
C0043515
Disease or Syndrome
2.

Multiple endocrine neoplasia

A group of autosomal dominant diseases characterized by the combined occurrence of tumors involving two or more ENDOCRINE GLANDS that secrete PEPTIDE HORMONES or AMINES. These neoplasias are often benign but can be malignant. They are classified by the endocrine glands involved and the degree of aggressiveness. The two major forms are MEN1 and MEN2 with gene mutations on CHROMOSOME 11 and CHROMOSOME 10, respectively. [from MeSH]

MedGen UID:
45036
Concept ID:
C0027662
Neoplastic Process
3.

Zollinger-Ellison syndrome

Zollinger-Ellison syndrome (ZES) is characterized by severe peptic disease (ulcers/esophageal disease) caused by hypergastrinemia secondary to a gastrinoma resulting in increased gastric acid secretion. [from ORDO]

MedGen UID:
797543
Concept ID:
CN206461
Disease or Syndrome
4.

Neoplasm of the endocrine system

A benign or malignant neoplasm arising from the epithelial cells of an endocrine organ. Representative examples include pituitary gland adenoma, pituitary gland carcinoma, thyroid gland carcinoma, carcinoid tumor, and neuroendocrine carcinoma. [from NCI]

MedGen UID:
4044
Concept ID:
C0014132
Neoplastic Process
5.

Abnormality of the anterior pituitary

An abnormality of the adenohypophysis, which is also known as the anterior lobe of the pituitary gland. [from HPO]

MedGen UID:
892315
Concept ID:
C4023206
Anatomical Abnormality
6.

Pancreatic endocrine tumor

A neoplasm with neuroendocrine differentiation that arises from the pancreas. It includes neuroendocrine tumors (low and intermediate grade) and neuroendocrine carcinomas (high grade). [from NCI]

MedGen UID:
66883
Concept ID:
C0242363
Neoplastic Process
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