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Items: 1 to 20 of 44

1.

Prolactin

A lactogenic hormone secreted by the adenohypophysis (PITUITARY GLAND, ANTERIOR). It is a polypeptide of approximately 23 kD. Besides its major action on lactation, in some species prolactin exerts effects on reproduction, maternal behavior, fat metabolism, immunomodulation and osmoregulation. Prolactin receptors are present in the mammary gland, hypothalamus, liver, ovary, testis, and prostate. [from MeSH]

MedGen UID:
46130
Concept ID:
C0033371
Amino Acid, Peptide, or Protein; Hormone; Pharmacologic Substance
2.

Thyrotrophin product

A glycoprotein hormone secreted by the adenohypophysis (PITUITARY GLAND, ANTERIOR). Thyrotropin stimulates THYROID GLAND by increasing the iodide transport, synthesis and release of thyroid hormones (THYROXINE and TRIIODOTHYRONINE). Thyrotropin consists of two noncovalently linked subunits, alpha and beta. Within a species, the alpha subunit is common in the pituitary glycoprotein hormones (TSH; LUTEINIZING HORMONE and FSH), but the beta subunit is unique and confers its biological specificity. [from MeSH]

MedGen UID:
21551
Concept ID:
C0040160
Amino Acid, Peptide, or Protein; Hormone; Pharmacologic Substance
3.

Thyrotropin releasing factor agent

A tripeptide that stimulates the release of THYROTROPIN and PROLACTIN. It is synthesized by the neurons in the PARAVENTRICULAR NUCLEUS of the HYPOTHALAMUS. After being released into the pituitary portal circulation, TRH (was called TRF) stimulates the release of TSH and PRL from the ANTERIOR PITUITARY GLAND. [from MeSH]

MedGen UID:
21175
Concept ID:
C0040162
Amino Acid, Peptide, or Protein; Hormone; Pharmacologic Substance
4.

AGON

Used with chemicals, drugs, and endogenous substances to indicate substances or agents that have affinity for a receptor and intrinsic activity at that receptor. (From Textbook of Pharmacology, 1991, p.16) [from MeSH]

MedGen UID:
116746
Concept ID:
C0243192
Pharmacologic Substance
5.

Myristate

14 carbon straight chain saturated fatty acid common in membrane phospholipids and fatty acylated proteins. [from CRISP]

MedGen UID:
51290
Concept ID:
C0129533
Biologically Active Substance; Organic Chemical; Pharmacologic Substance
6.

Ionomycin

A divalent calcium ionophore that is widely used as a tool to investigate the role of intracellular calcium in cellular processes. [from MeSH]

MedGen UID:
5887
Concept ID:
C0022020
Organic Chemical; Pharmacologic Substance
7.

Bay-K-8644

MedGen UID:
2181
Concept ID:
C0004855
Organic Chemical; Pharmacologic Substance
8.

Calcium

A basic element found in nearly all organized tissues. It is a member of the alkaline earth family of metals with the atomic symbol Ca, atomic number 20, and atomic weight 40. Calcium is the most abundant mineral in the body and combines with phosphorus to form calcium phosphate in the bones and teeth. It is essential for the normal functioning of nerves and muscles and plays a role in blood coagulation (as factor IV) and in many enzymatic processes. [from MeSH]

MedGen UID:
710
Concept ID:
C0006675
Biologically Active Substance; Element, Ion, or Isotope; Pharmacologic Substance
9.

Acetate compound

Salt or ester form of acetic acid. Acetate is the most common building block for biosynthesis, such as fatty acids. [from NCI]

MedGen UID:
452099
Concept ID:
C0000975
Organic Chemical; Pharmacologic Substance
10.

Dystonia 10

PRRT2-associated paroxysmal movement disorders (PRRT2-PxMD) include paroxysmal kinesigenic dyskinesia (PKD), benign familial infantile epilepsy (BFIE), paroxysmal kinesigenic dyskinesia with infantile convulsions (PKD/IC), and hemiplegic migraine (HM). In addition, PRRT2 pathogenic variants have been identified in other childhood-onset movement disorders and different types of seizures, suggesting that the understanding of the spectrum of PRRT2-PxMD is still evolving. The paroxysmal attacks in PKD are characterized by dystonia, choreoathetosis, and less commonly ballismus. The seizures of BFIE are usually focal with or without generalization. Thirty percent of PRRT2-associated PKD is associated with BFIE and is referred to as PKD/IC. [from GeneReviews]

MedGen UID:
358268
Concept ID:
C1868682
Disease or Syndrome
11.

Transmission

A passage or transfer, as of a disease from one individual to another. [from NCI]

MedGen UID:
66979
Concept ID:
C0242781
Pathologic Function
12.

Acute

Sudden appearance of disease manifestations over a short period of time. [from HPO]

MedGen UID:
61381
Concept ID:
C0205178
Temporal Concept
13.

Thyroliberin

MedGen UID:
438197
Concept ID:
C2713581
Amino Acid, Peptide, or Protein; Pharmacologic Substance
14.

Stimu-TSH

MedGen UID:
398827
Concept ID:
C2713580
Amino Acid, Peptide, or Protein; Pharmacologic Substance
15.

Antepan

MedGen UID:
398826
Concept ID:
C2713578
Amino Acid, Peptide, or Protein; Pharmacologic Substance
16.

Intracranial Neoplasm

A benign or malignant neoplasm that arises from or metastasizes to structures within the cranium. This includes meningeal and other tumors that occur in the spaces that surround the brain, and neoplasms of the brain. [from NCI]

MedGen UID:
287152
Concept ID:
C1527390
Neoplastic Process
17.

Colforsin

Potent activator of the adenylate cyclase system and the biosynthesis of cyclic AMP. From the plant COLEUS FORSKOHLII. Has antihypertensive, positive inotropic, platelet aggregation inhibitory, and smooth muscle relaxant activities; also lowers intraocular pressure and promotes release of hormones from the pituitary gland. [from MeSH]

MedGen UID:
214628
Concept ID:
C0917964
Organic Chemical; Pharmacologic Substance
18.

SQ-23377

MedGen UID:
168012
Concept ID:
C0878324
Organic Chemical; Pharmacologic Substance
19.

Malignant Supratentorial Neoplasm

MedGen UID:
155589
Concept ID:
C0751589
Neoplastic Process
20.

Thypinone

MedGen UID:
152007
Concept ID:
C0699184
Amino Acid, Peptide, or Protein; Pharmacologic Substance
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