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Items: 4

1.

Purpura

Purpura (from Latin: purpura, meaning \ [from HPO]

MedGen UID:
19584
Concept ID:
C0034150
Disease or Syndrome; Finding
2.

Immunoglobulin A vasculitis

Schönlein-Henoch purpura (SHP) is a systemic IgA vasculitis that affects small vessels. It is characterized by skin purpura, arthritis, and abdominal and/or renal involvement. [from ORDO]

MedGen UID:
799309
Concept ID:
CN205724
Finding
3.

Immunoglobulin A, Human

IgA is the immunoglobulin subclass that is associated with antibody-mediated mucosal immunity. It is secreted as dimers into the mucosa and is the most effective isotype at fixing complement by the alternative pathway, even though it lacks the ability to fix complement by the classical pathway. There are two subtypes in the human - IgA1 and IgA2. [from NCI]

MedGen UID:
442957
Concept ID:
C2825347
Immunologic Factor; Pharmacologic Substance
4.

Henoch-Schönlein purpura

A systemic, usually self-limited immune complex vasculitis, characterized by immunoglobulin A deposition in the small vessels and kidneys. It is manifested with small hemorrhages in the skin, gastrointestinal symptoms, arthritis, and nephropathy. [from NCI]

MedGen UID:
48265
Concept ID:
C0034152
Disease or Syndrome
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