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Cyclothymic Disorder

MedGen UID:
1198
Concept ID:
C0010598
Mental or Behavioral Dysfunction
Synonyms: Cyclothymic Disorders; Cyclothymic Personalities; Cyclothymic Personality; Disorder, Cyclothymic; Disorders, Cyclothymic; Personalities, Cyclothymic; Personality, Cyclothymic
SNOMED CT: Cyclothymia (76105009); Cyclothymic disorder (76105009); Affective personality trait (386798001); Cycloid personality (386798001); Unstable personality trait (386798001); Tends to be unstable in affect (386798001); Cyclothymic personality (386798001); Affective personality disorder (76105009)
 

Definition

An affective disorder characterized by periods of depression and hypomania. These may be separated by periods of normal mood. [from MeSH]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVCyclothymic Disorder

Recent clinical studies

Etiology

Van Meter AR, Youngstrom EA, Birmaher B, Fristad MA, Horwitz SM, Frazier TW, Arnold LE, Findling RL
J Affect Disord 2017 Jun;215:314-322. Epub 2017 Mar 14 doi: 10.1016/j.jad.2017.03.019. PMID: 28365522Free PMC Article
Perugi G, Hantouche E, Vannucchi G, Pinto O
J Affect Disord 2015 Sep 1;183:119-33. Epub 2015 May 13 doi: 10.1016/j.jad.2015.05.004. PMID: 26005206
Van Meter A, Youngstrom EA, Demeter C, Findling RL
J Abnorm Child Psychol 2013 Apr;41(3):367-78. doi: 10.1007/s10802-012-9680-1. PMID: 22968491
Van Meter AR, Youngstrom EA, Findling RL
Clin Psychol Rev 2012 Jun;32(4):229-43. Epub 2012 Feb 10 doi: 10.1016/j.cpr.2012.02.001. PMID: 22459786
Fava GA, Rafanelli C, Tomba E, Guidi J, Grandi S
Psychother Psychosom 2011;80(3):136-43. Epub 2011 Mar 3 doi: 10.1159/000321575. PMID: 21372621

Diagnosis

Van Meter AR, Youngstrom EA, Birmaher B, Fristad MA, Horwitz SM, Frazier TW, Arnold LE, Findling RL
J Affect Disord 2017 Jun;215:314-322. Epub 2017 Mar 14 doi: 10.1016/j.jad.2017.03.019. PMID: 28365522Free PMC Article
Van Meter A, Youngstrom E, Freeman A, Feeny N, Youngstrom JK, Findling RL
J Child Adolesc Psychopharmacol 2016 Feb;26(1):26-37. Epub 2016 Feb 2 doi: 10.1089/cap.2015.0111. PMID: 26835744Free PMC Article
Van Meter A, Youngstrom EA, Demeter C, Findling RL
J Abnorm Child Psychol 2013 Apr;41(3):367-78. doi: 10.1007/s10802-012-9680-1. PMID: 22968491
Van Meter AR, Youngstrom EA, Findling RL
Clin Psychol Rev 2012 Jun;32(4):229-43. Epub 2012 Feb 10 doi: 10.1016/j.cpr.2012.02.001. PMID: 22459786
Van Meter A, Youngstrom EA, Youngstrom JK, Feeny NC, Findling RL
J Affect Disord 2011 Jul;132(1-2):55-63. Epub 2011 Mar 11 doi: 10.1016/j.jad.2011.02.004. PMID: 21396717Free PMC Article

Therapy

Van Meter AR, Youngstrom EA, Birmaher B, Fristad MA, Horwitz SM, Frazier TW, Arnold LE, Findling RL
J Affect Disord 2017 Jun;215:314-322. Epub 2017 Mar 14 doi: 10.1016/j.jad.2017.03.019. PMID: 28365522Free PMC Article
Fristad MA, Young AS, Vesco AT, Nader ES, Healy KZ, Gardner W, Wolfson HL, Arnold LE
J Child Adolesc Psychopharmacol 2015 Dec;25(10):764-74. doi: 10.1089/cap.2015.0132. PMID: 26682997Free PMC Article
Fava GA, Rafanelli C, Tomba E, Guidi J, Grandi S
Psychother Psychosom 2011;80(3):136-43. Epub 2011 Mar 3 doi: 10.1159/000321575. PMID: 21372621
Baldessarini RJ, Vázquez G, Tondo L
Psychother Psychosom 2011;80(3):131-5. Epub 2011 Mar 3 doi: 10.1159/000322234. PMID: 21372620
Mazza M, Mandelli L, Di Nicola M, Harnic D, Catalano V, Tedeschi D, Martinotti G, Colombo R, Bria P, Serretti A, Janiri L
J Affect Disord 2009 May;115(1-2):27-35. Epub 2008 Oct 8 doi: 10.1016/j.jad.2008.08.019. PMID: 18845344

Prognosis

Van Meter AR, Youngstrom EA, Birmaher B, Fristad MA, Horwitz SM, Frazier TW, Arnold LE, Findling RL
J Affect Disord 2017 Jun;215:314-322. Epub 2017 Mar 14 doi: 10.1016/j.jad.2017.03.019. PMID: 28365522Free PMC Article
Perugi G, Hantouche E, Vannucchi G, Pinto O
J Affect Disord 2015 Sep 1;183:119-33. Epub 2015 May 13 doi: 10.1016/j.jad.2015.05.004. PMID: 26005206
Van Meter AR, Youngstrom EA, Findling RL
Clin Psychol Rev 2012 Jun;32(4):229-43. Epub 2012 Feb 10 doi: 10.1016/j.cpr.2012.02.001. PMID: 22459786
Van Meter A, Youngstrom EA, Youngstrom JK, Feeny NC, Findling RL
J Affect Disord 2011 Jul;132(1-2):55-63. Epub 2011 Mar 11 doi: 10.1016/j.jad.2011.02.004. PMID: 21396717Free PMC Article
Fava GA, Rafanelli C, Tomba E, Guidi J, Grandi S
Psychother Psychosom 2011;80(3):136-43. Epub 2011 Mar 3 doi: 10.1159/000321575. PMID: 21372621

Clinical prediction guides

Van Meter AR, Youngstrom EA, Birmaher B, Fristad MA, Horwitz SM, Frazier TW, Arnold LE, Findling RL
J Affect Disord 2017 Jun;215:314-322. Epub 2017 Mar 14 doi: 10.1016/j.jad.2017.03.019. PMID: 28365522Free PMC Article
Van Meter A, Youngstrom E, Freeman A, Feeny N, Youngstrom JK, Findling RL
J Child Adolesc Psychopharmacol 2016 Feb;26(1):26-37. Epub 2016 Feb 2 doi: 10.1089/cap.2015.0111. PMID: 26835744Free PMC Article
Harnic D, Pompili M, Innamorati M, Erbuto D, Lamis DA, Bria P, Girardi P, Janiri L
Compr Psychiatry 2014 May;55(4):999-1006. Epub 2013 Dec 10 doi: 10.1016/j.comppsych.2013.12.006. PMID: 24411930
Tomba E, Rafanelli C, Grandi S, Guidi J, Fava GA
J Affect Disord 2012 Aug;139(3):244-9. Epub 2012 May 1 doi: 10.1016/j.jad.2012.01.014. PMID: 22551912
Fava GA, Rafanelli C, Tomba E, Guidi J, Grandi S
Psychother Psychosom 2011;80(3):136-43. Epub 2011 Mar 3 doi: 10.1159/000321575. PMID: 21372621

Recent systematic reviews

Solmi M, Zaninotto L, Toffanin T, Veronese N, Lin K, Stubbs B, Fornaro M, Correll CU
J Affect Disord 2016 May 15;196:32-46. Epub 2016 Feb 12 doi: 10.1016/j.jad.2016.02.013. PMID: 26897455
Van Meter AR, Burke C, Kowatch RA, Findling RL, Youngstrom EA
Bipolar Disord 2016 Feb;18(1):19-32. Epub 2016 Jan 9 doi: 10.1111/bdi.12358. PMID: 26748678
Polyakova M, Stuke K, Schuemberg K, Mueller K, Schoenknecht P, Schroeter ML
J Affect Disord 2015 Mar 15;174:432-40. Epub 2014 Nov 29 doi: 10.1016/j.jad.2014.11.044. PMID: 25553404
Van Meter AR, Youngstrom EA, Findling RL
Clin Psychol Rev 2012 Jun;32(4):229-43. Epub 2012 Feb 10 doi: 10.1016/j.cpr.2012.02.001. PMID: 22459786
Ozgürdal S, van Haren E, Hauser M, Ströhle A, Bauer M, Assion HJ, Juckel G
Psychopathology 2009;42(5):337-42. Epub 2009 Aug 11 doi: 10.1159/000232977. PMID: 19672137

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