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Spasticity

MedGen UID:
504771
Concept ID:
CN001152
Finding
Synonyms: Muscle spasticity; Muscular spasticity
 

Definition

A motor disorder characterized by a velocity-dependent increase in tonic stretch reflexes with increased muscle tone, exaggerated (hyperexcitable) tendon reflexes. [from HPO]

Recent clinical studies

Etiology

Wang J, Yu P, Zeng M, Gu X, Liu Y, Xiao M
Neurol Res 2017 Jan;39(1):36-44. Epub 2016 Nov 23 doi: 10.1080/01616412.2016.1248169. PMID: 27876449
Veverka T, Hluštík P, Hok P, Otruba P, Zapletalová J, Tüdös Z, Krobot A, Kaňovský P
J Neurol Sci 2016 Mar 15;362:14-20. Epub 2016 Jan 11 doi: 10.1016/j.jns.2015.12.049. PMID: 26944111
Slovak M, Chindo J, Nair KP, Reeves ML, Heller B, Barker AT
Neuromodulation 2016 Feb;19(2):220-6. doi: 10.1111/ner.12383. PMID: 26890016
Gras A, Broughton J
Expert Rev Pharmacoecon Outcomes Res 2016 Dec;16(6):771-779. Epub 2016 Feb 26 doi: 10.1586/14737167.2016.1140574. PMID: 26750641
Ferrè L, Nuara A, Pavan G, Radaelli M, Moiola L, Rodegher M, Colombo B, Keller Sarmiento IJ, Martinelli V, Leocani L, Martinelli Boneschi F, Comi G, Esposito F
Neurol Sci 2016 Feb;37(2):235-42. Epub 2015 Oct 16 doi: 10.1007/s10072-015-2392-x. PMID: 26474875

Diagnosis

Bhimani RH, Peden-McAlpine C, Gaugler J, Anderson LC
Appl Nurs Res 2016 May;30:16-23. Epub 2015 Aug 20 doi: 10.1016/j.apnr.2015.08.007. PMID: 27091247
Gómez-Soriano J, Bravo-Esteban E, Pérez-Rizo E, Ávila-Martín G, Galán-Arriero I, Simón-Martinez C, Taylor J
Spinal Cord 2016 Sep;54(9):687-94. Epub 2016 Feb 23 doi: 10.1038/sc.2016.9. PMID: 26902460
Wang ZM, Law JH, King NK, Rajeswaran DK, Soh S, Rao JP, Ng WH, Chua KS
Singapore Med J 2016 Jan;57(1):8-12. doi: 10.11622/smedj.2016005. PMID: 26831310Free PMC Article
Bethoux F
Phys Med Rehabil Clin N Am 2015 Nov;26(4):625-39. Epub 2015 Sep 26 doi: 10.1016/j.pmr.2015.07.003. PMID: 26522902
Nam HS, Park YG, Paik NJ, Oh BM, Chun MH, Yang HE, Kim DH, Yi Y, Seo HG, Kim KD, Chang MC, Ryu JH, Lee SU
J Neurol Sci 2015 Oct 15;357(1-2):192-7. Epub 2015 Jul 21 doi: 10.1016/j.jns.2015.07.028. PMID: 26233808

Therapy

Wang J, Yu P, Zeng M, Gu X, Liu Y, Xiao M
Neurol Res 2017 Jan;39(1):36-44. Epub 2016 Nov 23 doi: 10.1080/01616412.2016.1248169. PMID: 27876449
Ertzgaard P, Anhammer M, Forsmark A
Acta Neurol Scand 2017 Mar;135(3):366-372. Epub 2016 May 24 doi: 10.1111/ane.12610. PMID: 27220381
Veverka T, Hluštík P, Hok P, Otruba P, Zapletalová J, Tüdös Z, Krobot A, Kaňovský P
J Neurol Sci 2016 Mar 15;362:14-20. Epub 2016 Jan 11 doi: 10.1016/j.jns.2015.12.049. PMID: 26944111
Gras A, Broughton J
Expert Rev Pharmacoecon Outcomes Res 2016 Dec;16(6):771-779. Epub 2016 Feb 26 doi: 10.1586/14737167.2016.1140574. PMID: 26750641
Shaikh A, Phadke CP, Ismail F, Boulias C
Can J Neurol Sci 2016 Mar;43(2):311-5. Epub 2015 Dec 22 doi: 10.1017/cjn.2015.321. PMID: 26691344

Prognosis

Wang J, Yu P, Zeng M, Gu X, Liu Y, Xiao M
Neurol Res 2017 Jan;39(1):36-44. Epub 2016 Nov 23 doi: 10.1080/01616412.2016.1248169. PMID: 27876449
Veverka T, Hluštík P, Hok P, Otruba P, Zapletalová J, Tüdös Z, Krobot A, Kaňovský P
J Neurol Sci 2016 Mar 15;362:14-20. Epub 2016 Jan 11 doi: 10.1016/j.jns.2015.12.049. PMID: 26944111
Wang ZM, Law JH, King NK, Rajeswaran DK, Soh S, Rao JP, Ng WH, Chua KS
Singapore Med J 2016 Jan;57(1):8-12. doi: 10.11622/smedj.2016005. PMID: 26831310Free PMC Article
Dashtipour K, Chen JJ, Walker HW, Lee MY
Medicine (Baltimore) 2016 Jan;95(2):e2468. doi: 10.1097/MD.0000000000002468. PMID: 26765447Free PMC Article
Cheung DK, Climans SA, Black SE, Gao F, Szilagyi GM, Mochizuki G
Neurorehabil Neural Repair 2016 Jan;30(1):63-70. Epub 2015 May 20 doi: 10.1177/1545968315585357. PMID: 25995383

Clinical prediction guides

Illomei G, Spinicci G, Locci E, Marrosu MG
Neurol Sci 2017 Mar;38(3):433-439. Epub 2016 Nov 30 doi: 10.1007/s10072-016-2780-x. PMID: 27904961
Wang J, Yu P, Zeng M, Gu X, Liu Y, Xiao M
Neurol Res 2017 Jan;39(1):36-44. Epub 2016 Nov 23 doi: 10.1080/01616412.2016.1248169. PMID: 27876449
Milne SC, Corben LA, Yiu E, Delatycki MB, Georgiou-Karistianis N
J Clin Neurosci 2016 Jul;29:29-34. Epub 2016 Mar 25 doi: 10.1016/j.jocn.2016.01.011. PMID: 27021226
Veverka T, Hluštík P, Hok P, Otruba P, Zapletalová J, Tüdös Z, Krobot A, Kaňovský P
J Neurol Sci 2016 Mar 15;362:14-20. Epub 2016 Jan 11 doi: 10.1016/j.jns.2015.12.049. PMID: 26944111
Ferrè L, Nuara A, Pavan G, Radaelli M, Moiola L, Rodegher M, Colombo B, Keller Sarmiento IJ, Martinelli V, Leocani L, Martinelli Boneschi F, Comi G, Esposito F
Neurol Sci 2016 Feb;37(2):235-42. Epub 2015 Oct 16 doi: 10.1007/s10072-015-2392-x. PMID: 26474875

Recent systematic reviews

Lindsay C, Kouzouna A, Simcox C, Pandyan AD
Cochrane Database Syst Rev 2016 Oct 6;10:CD010362. doi: 10.1002/14651858.CD010362.pub2. PMID: 27711973
Dashtipour K, Chen JJ, Walker HW, Lee MY
Medicine (Baltimore) 2016 Jan;95(2):e2468. doi: 10.1097/MD.0000000000002468. PMID: 26765447Free PMC Article
Dressler D, Rychlik R, Kreimendahl F, Schnur N, Lambert-Baumann J
BMJ Open 2015 Dec 30;5(12):e009358. doi: 10.1136/bmjopen-2015-009358. PMID: 26719317Free PMC Article
Hasnat MJ, Rice JE
Cochrane Database Syst Rev 2015 Nov 13;(11):CD004552. doi: 10.1002/14651858.CD004552.pub2. PMID: 26563961
Aloraini SM, Gäverth J, Yeung E, MacKay-Lyons M
Disabil Rehabil 2015;37(25):2313-23. Epub 2015 Feb 18 doi: 10.3109/09638288.2015.1014933. PMID: 25690684

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