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Items: 7

1.

Interferon beta

A class of interferon elaborated by fibroblasts. [from NCI]

MedGen UID:
5171
Concept ID:
C0015980
Amino Acid, Peptide, or Protein; Immunologic Factor; Pharmacologic Substance
2.

Interferon

Human interferons have been classified into 3 groups: alpha, beta, and gamma. Both alpha- and beta-IFNs, previously designated type I, are acid-stable, but they differ immunologically and in regard to some biologic and physiochemical properties. The IFNs produced by virus-stimulated leukocytes (leukocyte IFNs) are predominantly of the alpha type. Those produced by lymphoblastoid cells are about 90% alpha and 10% beta. Induced fibroblasts produce mainly or exclusively the beta type. The alpha- and beta-IFNs differ widely in amino acid sequence. The gamma or immune IFNs, which are produced by T lymphocytes in response to mitogens or to antigens to which they are sensitized, are acid-labile and serologically distinct from alpha- and beta-IFNs. (from OMIM 147570) [from NCI]

MedGen UID:
196514
Concept ID:
C0733470
Amino Acid, Peptide, or Protein; Immunologic Factor; Pharmacologic Substance
3.

Lesion

A localized pathological or traumatic structural change, damage, deformity, or discontinuity of tissue, organ, or body part. [from NCI]

MedGen UID:
65128
Concept ID:
C0221198
Finding
4.

Interferon

Proteins secreted by vertebrate cells in response to a wide variety of inducers. They confer resistance against many different viruses, inhibit proliferation of normal and malignant cells, impede multiplication of intracellular parasites, enhance macrophage and granulocyte phagocytosis, augment natural killer cell activity, and show several other immunomodulatory functions. [from MeSH]

MedGen UID:
5847
Concept ID:
C0021747
Amino Acid, Peptide, or Protein; Immunologic Factor; Pharmacologic Substance
5.

Pen, Avonex

MedGen UID:
854039
Concept ID:
C3473060
Amino Acid, Peptide, or Protein; Immunologic Factor; Pharmacologic Substance
6.

Rebif

MedGen UID:
156324
Concept ID:
C0752980
Amino Acid, Peptide, or Protein; Pharmacologic Substance
7.

Avonex

MedGen UID:
108554
Concept ID:
C0594372
Amino Acid, Peptide, or Protein; Immunologic Factor; Pharmacologic Substance
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