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Items: 4

1.

Adalimumab

A humanized monoclonal antibody that binds specifically to TNF-ALPHA and blocks its interaction with endogenous TNF RECEPTORS to modulate INFLAMMATION. It is used in the treatment of RHEUMATOID ARTHRITIS; PSORIATIC ARTHRITIS; CROHN'S DISEASE and ULCERATIVE COLITIS. [from MeSH]

MedGen UID:
207641
Concept ID:
C1122087
Amino Acid, Peptide, or Protein; Immunologic Factor; Pharmacologic Substance
2.

Etanercept

A recombinant soluble dimeric fusion protein consisting of the extracellular ligand-binding region of recombinant human tumor necrosis factor (rhTNF) receptor attached to the constant (Fc) region of human immunoglobulin G (FcIgG). The receptor moiety of etanercept binds to circulating TNF (2 molecules of TNF per receptor) and inhibits its attachment to endogenous TNF cell surface receptors, thereby rendering TNF inactive and inhibiting TNF-mediated mechanisms of inflammation. (NCI04) [from NCI]

MedGen UID:
152404
Concept ID:
C0717758
Amino Acid, Peptide, or Protein; Pharmacologic Substance
3.

Psoriasis

A common genetically determined, chronic, inflammatory skin disease characterized by rounded erythematous, dry, scaling patches. The lesions have a predilection for nails, scalp, genitalia, extensor surfaces, and the lumbosacral region. Accelerated epidermopoiesis is considered to be the fundamental pathologic feature in psoriasis. [from MeSH]

MedGen UID:
10997
Concept ID:
C0033860
Disease or Syndrome
4.

Psoriasis

A skin abnormality characterized by redness and irritation, with thick, red skin that displays flaky, silver-white patches (scales). [from HPO]

MedGen UID:
505592
Concept ID:
CN003401
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