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Items: 7

1.

Leiomyoma

A benign tumor derived from smooth muscle tissue, also known as a fibroid tumor. They rarely occur outside of the UTERUS and the GASTROINTESTINAL TRACT but can occur in the SKIN and SUBCUTANEOUS TISSUE, probably arising from the smooth muscle of small blood vessels in these tissues. [from MeSH]

MedGen UID:
9710
Concept ID:
C0023267
Neoplastic Process
2.

Uterine leiomyoma

The presence of a leiomyoma of the uterus. [from HPO]

MedGen UID:
504355
Concept ID:
CN000127
Finding
3.

Possible

Capable of happening or occurring. [from NCI]

MedGen UID:
137646
Concept ID:
C0332149
Finding
4.

Uterine leiomyoma

Uterine fibroids are the most common benign tumors in women of childbearing age. Fibroids are made of muscle cells and other tissues that grow in and around the wall of the uterus, or womb. The cause of fibroids is unknown. Risk factors include being African American or being overweight. Many women with fibroids have no symptoms. If you do have symptoms, they may include. -Heavy or painful periods or bleeding between periods . -Feeling full in the lower abdomen . -Urinating often . -Pain during sex . -Lower back pain . -Reproductive problems, such as infertility, multiple miscarriages or early labor. Your health care provider may find fibroids during a gynecological exam or by using imaging tests. Treatment includes drugs that can slow or stop their growth, or surgery. If you have no symptoms, you may not even need treatment. Many women with fibroids can get pregnant naturally. For those who cannot, infertility treatments may help. NIH: National Institute of Child Health and Human Development.  [from MedlinePlus]

MedGen UID:
21801
Concept ID:
C0042133
Neoplastic Process
5.

Ulipristal acetate

An orally bioavailable, acetate salt of ulipristal, a selective progesterone receptor modulator with anti-progesterone activity. Ulipristal binds to the progesterone receptor (PR), thereby inhibiting PR-mediated gene expression, and interfering with progesterone activity in the reproductive system. As a result, this agent may suppress the growth of uterine leiomyomatosis. Furthermore, by inhibiting or delaying ovulation and effecting endometrial tissue, ulipristal can be used as an emergency contraception [from NCI]

MedGen UID:
404769
Concept ID:
C2723461
Organic Chemical; Pharmacologic Substance
6.

asoprisnil

MedGen UID:
265258
Concept ID:
C1455381
Organic Chemical; Pharmacologic Substance
7.

ulipristal

A selective progesterone receptor modulator with anti-progesterone activity. Ulipristal binds to the progesterone receptor (PR), thereby inhibiting PR-mediated gene expression, and interfering with progesterone activity in the reproductive system. As a result, this agent may suppress the growth of uterine leiomyomatosis. Furthermore, by inhibiting or delaying ovulation and effecting endometrial tissue, ulipristal can be used as an emergency contraception. [from NCI]

MedGen UID:
90050
Concept ID:
C0300205
Organic Chemical; Pharmacologic Substance
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