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Anal Carcinoma

MedGen UID:
76006
Concept ID:
C0279637
Neoplastic Process
Synonyms: Anal Cancer; Anal Cancers; Anus Cancer; Anus Cancers; Cancer of Anus; Cancer of the Anus; Cancer, Anal; Cancers, Anal
SNOMED CT: Anal carcinoma (255084004)
 

Definition

A carcinoma that arises from the anus. Anal carcinomas include the anal canal and anal margin (perianal skin) carcinomas. The anal margin carcinoma is staged separately as a skin carcinoma. Anal cancer stage terms are used as synonyms for anal canal cancer stage terms. [from NCI]

Term Hierarchy

Recent clinical studies

Etiology

Mohammadkhani Shali S, Schmitt V, Behrendt FF, Winz OH, Heinzel A, Mottaghy FM, Eble MJ, Verburg FA
Eur J Radiol 2016 Aug;85(8):1390-4. Epub 2016 May 20 doi: 10.1016/j.ejrad.2016.05.009. PMID: 27423677
Hardt J, Mai S, Weiß C, Kienle P, Magdeburg J
Int J Colorectal Dis 2016 Jun;31(6):1197-203. Epub 2016 Mar 31 doi: 10.1007/s00384-016-2575-9. PMID: 27033699
Weber HE, Dröge LH, Hennies S, Herrmann MK, Gaedcke J, Wolff HA
Strahlenther Onkol 2015 Nov;191(11):827-34. Epub 2015 Jun 8 doi: 10.1007/s00066-015-0859-6. PMID: 26050046
Mistrangelo M, Senetta R, Racca P, Castellano I, Chiusa L, Bellò M, Ricardi U, Morino M, Cassoni P
Colorectal Dis 2013 Nov;15(11):1382-91. doi: 10.1111/codi.12289. PMID: 23692332
Legarth R, Helleberg M, Kronborg G, Larsen CS, Pedersen G, Pedersen C, Jensen J, Nielsen LN, Gerstoft J, Obel N
Scand J Infect Dis 2013 Jun;45(6):453-9. Epub 2013 Jan 7 doi: 10.3109/00365548.2012.737476. PMID: 23294033

Diagnosis

Bjekic M, Sipetic-Grujicic S, Dunic I, Salemovic D, Vlajinac H
Int J Dermatol 2016 Oct;55(10):1082-7. Epub 2016 Jun 3 doi: 10.1111/ijd.13338. PMID: 27260829
Raptis D, Schneider I, Matzel KE, Ott O, Fietkau R, Hohenberger W
Dtsch Arztebl Int 2015 Apr 3;112(14):243-9. doi: 10.3238/arztebl.2015.0243. PMID: 25891807Free PMC Article
Herranz-Pinto P, Sendagorta-Cudós E, Bernardino-de la Serna JI, Peña-Sánchez de Rivera JM
Rev Clin Esp (Barc) 2014 Mar;214(2):87-93. Epub 2013 Oct 16 doi: 10.1016/j.rce.2013.08.011. PMID: 24139082
Legarth R, Helleberg M, Kronborg G, Larsen CS, Pedersen G, Pedersen C, Jensen J, Nielsen LN, Gerstoft J, Obel N
Scand J Infect Dis 2013 Jun;45(6):453-9. Epub 2013 Jan 7 doi: 10.3109/00365548.2012.737476. PMID: 23294033
Benson AB 3rd, Arnoletti JP, Bekaii-Saab T, Chan E, Chen YJ, Choti MA, Cooper HS, Dilawari RA, Engstrom PF, Enzinger PC, Fakih MG, Fleshman JW Jr, Fuchs CS, Grem JL, Leong LA, Lin E, May KS, Mulcahy MF, Murphy K, Rohren E, Ryan DP, Saltz L, Sharma S, Shibata D, Skibber JM, Small W Jr, Sofocleous CT, Venook AP, Willett C, Freedman-Cass DA; National Comprehensive Cancer Network.
J Natl Compr Canc Netw 2012 Apr;10(4):449-54. PMID: 22491045

Therapy

Sauter M, Vavricka SR, Keilholz G, Heinrich H, Winder T, Kranzbühler H, Lombriser N, Misselwitz B
Strahlenther Onkol 2017 Aug;193(8):639-647. Epub 2017 Jun 26 doi: 10.1007/s00066-017-1159-0. PMID: 28653119
Mohammadkhani Shali S, Schmitt V, Behrendt FF, Winz OH, Heinzel A, Mottaghy FM, Eble MJ, Verburg FA
Eur J Radiol 2016 Aug;85(8):1390-4. Epub 2016 May 20 doi: 10.1016/j.ejrad.2016.05.009. PMID: 27423677
Weber HE, Dröge LH, Hennies S, Herrmann MK, Gaedcke J, Wolff HA
Strahlenther Onkol 2015 Nov;191(11):827-34. Epub 2015 Jun 8 doi: 10.1007/s00066-015-0859-6. PMID: 26050046
Munoz-Bongrand N, Poghosyan T, Zohar S, Gerard L, Chirica M, Quero L, Gornet JM, Cattan P
Dis Colon Rectum 2011 Jun;54(6):729-35. doi: 10.1007/DCR.0b013e3182137de9. PMID: 21552058
Kreuter A, Potthoff A, Brockmeyer NH, Gambichler T, Swoboda J, Stücker M, Schmitt M, Pfister H, Wieland U; German Competence Network HIV/AIDS.
Br J Dermatol 2010 Jun;162(6):1269-77. Epub 2010 Feb 22 doi: 10.1111/j.1365-2133.2010.09712.x. PMID: 20184584

Prognosis

Mohammadkhani Shali S, Schmitt V, Behrendt FF, Winz OH, Heinzel A, Mottaghy FM, Eble MJ, Verburg FA
Eur J Radiol 2016 Aug;85(8):1390-4. Epub 2016 May 20 doi: 10.1016/j.ejrad.2016.05.009. PMID: 27423677
Weber HE, Dröge LH, Hennies S, Herrmann MK, Gaedcke J, Wolff HA
Strahlenther Onkol 2015 Nov;191(11):827-34. Epub 2015 Jun 8 doi: 10.1007/s00066-015-0859-6. PMID: 26050046
Mistrangelo M, Senetta R, Racca P, Castellano I, Chiusa L, Bellò M, Ricardi U, Morino M, Cassoni P
Colorectal Dis 2013 Nov;15(11):1382-91. doi: 10.1111/codi.12289. PMID: 23692332
Legarth R, Helleberg M, Kronborg G, Larsen CS, Pedersen G, Pedersen C, Jensen J, Nielsen LN, Gerstoft J, Obel N
Scand J Infect Dis 2013 Jun;45(6):453-9. Epub 2013 Jan 7 doi: 10.3109/00365548.2012.737476. PMID: 23294033
Kreuter A, Potthoff A, Brockmeyer NH, Gambichler T, Swoboda J, Stücker M, Schmitt M, Pfister H, Wieland U; German Competence Network HIV/AIDS.
Br J Dermatol 2010 Jun;162(6):1269-77. Epub 2010 Feb 22 doi: 10.1111/j.1365-2133.2010.09712.x. PMID: 20184584

Clinical prediction guides

Mohammadkhani Shali S, Schmitt V, Behrendt FF, Winz OH, Heinzel A, Mottaghy FM, Eble MJ, Verburg FA
Eur J Radiol 2016 Aug;85(8):1390-4. Epub 2016 May 20 doi: 10.1016/j.ejrad.2016.05.009. PMID: 27423677
Goldman KE, White EC, Rao AR, Kaptein JS, Lien WW
Pract Radiat Oncol 2016 Sep-Oct;6(5):e149-54. Epub 2016 Jan 12 doi: 10.1016/j.prro.2016.01.004. PMID: 26948134
Blinde SE, Schasfoort R, Mens JW, Verhoef C, Olofsen M, Nuyttens JJ
Dis Colon Rectum 2014 May;57(5):578-84. doi: 10.1097/DCR.0000000000000050. PMID: 24819097
Mistrangelo M, Senetta R, Racca P, Castellano I, Chiusa L, Bellò M, Ricardi U, Morino M, Cassoni P
Colorectal Dis 2013 Nov;15(11):1382-91. doi: 10.1111/codi.12289. PMID: 23692332
Kreuter A, Potthoff A, Brockmeyer NH, Gambichler T, Swoboda J, Stücker M, Schmitt M, Pfister H, Wieland U; German Competence Network HIV/AIDS.
Br J Dermatol 2010 Jun;162(6):1269-77. Epub 2010 Feb 22 doi: 10.1111/j.1365-2133.2010.09712.x. PMID: 20184584

Recent systematic reviews

Raptis D, Schneider I, Matzel KE, Ott O, Fietkau R, Hohenberger W
Dtsch Arztebl Int 2015 Apr 3;112(14):243-9. doi: 10.3238/arztebl.2015.0243. PMID: 25891807Free PMC Article
Giani I, Mistrangelo M, Fucini C; Italian Society of Colo-Rectal Surgery.
Tech Coloproctol 2013 Apr;17(2):171-9. Epub 2012 Nov 10 doi: 10.1007/s10151-012-0912-8. PMID: 23143219
Benson AB 3rd, Arnoletti JP, Bekaii-Saab T, Chan E, Chen YJ, Choti MA, Cooper HS, Dilawari RA, Engstrom PF, Enzinger PC, Fakih MG, Fleshman JW Jr, Fuchs CS, Grem JL, Leong LA, Lin E, May KS, Mulcahy MF, Murphy K, Rohren E, Ryan DP, Saltz L, Sharma S, Shibata D, Skibber JM, Small W Jr, Sofocleous CT, Venook AP, Willett C, Freedman-Cass DA; National Comprehensive Cancer Network.
J Natl Compr Canc Netw 2012 Apr;10(4):449-54. PMID: 22491045
Nguyen NP, Vock J, Sroka T, Khan R, Jang S, Chi A, Betz M, Ewell L, Cohen D, Vo RP, Mills M, Vinh-Hung V
Anticancer Res 2011 Dec;31(12):4393-6. PMID: 22199304
Engstrom PF, Arnoletti JP, Benson AB 3rd, Berlin JD, Berry JM, Chen YJ, Choti MA, Cooper HS, Dilawari RA, Early DS, Enzinger PC, Fakih MG, Fleshman J Jr, Fuchs C, Grem JL, Knol JA, Leong LA, Lin E, Mulcahy MF, Rohren E, Ryan DP, Saltz L, Shibata D, Skibber JM, Small W, Sofocleous C, Thomas J, Venook AP, Willett C; NCCN.
J Natl Compr Canc Netw 2010 Jan;8(1):106-20. PMID: 20064293

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