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Items: 9

1.

Vinegar

MedGen UID:
101661
Concept ID:
C0148405
Indicator, Reagent, or Diagnostic Aid; Organic Chemical; Pharmacologic Substance
2.

Parafon

MedGen UID:
327845
Concept ID:
C1564758
Organic Chemical; Pharmacologic Substance
3.

Dapsoderm-X

MedGen UID:
298443
Concept ID:
C1569265
Organic Chemical; Pharmacologic Substance
4.

Sulfona

MedGen UID:
293897
Concept ID:
C1569263
Organic Chemical; Pharmacologic Substance
5.

Dapson-Fatol

MedGen UID:
292192
Concept ID:
C1569264
Organic Chemical; Pharmacologic Substance
6.

Paraflex

MedGen UID:
208828
Concept ID:
C0813433
Organic Chemical; Pharmacologic Substance
7.

Avlosulfone

MedGen UID:
196428
Concept ID:
C0729115
Organic Chemical; Pharmacologic Substance
8.

Disulone

MedGen UID:
149062
Concept ID:
C0729116
Organic Chemical; Pharmacologic Substance
9.

Chlorzoxozone

A benzoxazolone derivative with mild sedative and centrally-acting muscle relaxant activities. Although its exact mechanism of action is unknown, chlorzoxazone (CZ) appears to act at the spinal cord and subcortical levels of the brain to inhibit multisynaptic reflex arcs involved in producing and maintaining muscle spasms. This agent is extensively hydroxylated by cytochrome P450 2E1 (CYP2E1) to 6-hydroxychlorzoxazone (HCZ),11,12 which is subsequently glucuronidated and eliminated renally. Highly selective for CYP2E1, CZ may be used as a selective probe for phenotyping CYP2E1 in humans; the ratio of HCZ-to-CZ plasma concentrations obtained 2 to 4 hours after oral administration of CZ may be used as a phenotypic measure of CYP2E1 enzymatic activity. [from NCI]

MedGen UID:
915
Concept ID:
C0008296
Organic Chemical; Pharmacologic Substance
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