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rasagiline

MedGen UID:
101293
Concept ID:
C0525678
Organic Chemical; Pharmacologic Substance
Synonyms: N-2-propynyl-1-indanamine
SNOMED CT: Rasagiline (418734001); Rasagiline (419010007)
 

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVrasagiline

Recent clinical studies

Etiology

Panisset M, Stril JL, Bélanger M, Lehoux G, Coffin D, Chouinard S
Can J Neurol Sci 2016 Nov;43(6):809-814. doi: 10.1017/cjn.2016.289. PMID: 27827298
Nuebling G, Hensler M, Paul S, Zwergal A, Crispin A, Lorenzl S
J Neurol 2016 Aug;263(8):1565-74. Epub 2016 May 26 doi: 10.1007/s00415-016-8169-1. PMID: 27230855
Masellis M, Collinson S, Freeman N, Tampakeras M, Levy J, Tchelet A, Eyal E, Berkovich E, Eliaz RE, Abler V, Grossman I, Fitzer-Attas C, Tiwari A, Hayden MR, Kennedy JL, Lang AE, Knight J; ADAGIO investigators.
Brain 2016 Jul;139(Pt 7):2050-62. Epub 2016 May 13 doi: 10.1093/brain/aww109. PMID: 27190009
Haehner A, Habersack A, Wienecke M, Storch A, Reichmann H, Hummel T
J Neural Transm (Vienna) 2015 Nov;122(11):1541-6. Epub 2015 Jul 30 doi: 10.1007/s00702-015-1433-1. PMID: 26224038
Macchi Z, Wang Y, Moore D, Katz J, Saperstein D, Walk D, Simpson E, Genge A, Bertorini T, Fernandes JA, Swenson A, Elman L, Dimachkie M, Herbelin L, Miller J, Lu J, Wilkins H, Swerdlow RH, Statland J, Barohn R; Western ALS (WALS) Rasagiline Study Group.
Amyotroph Lateral Scler Frontotemporal Degener 2015;16(5-6):345-52. Epub 2015 Apr 2 doi: 10.3109/21678421.2015.1026826. PMID: 25832828Free PMC Article

Diagnosis

Ibrahim FA, Rashid F, Hussain AA, Alawadi F, Bashier A
J Med Case Rep 2017 Feb 2;11(1):29. doi: 10.1186/s13256-017-1202-x. PMID: 28148284Free PMC Article
Degli Esposti L, Piccinni C, Sangiorgi D, Nobili F, Buda S
Neurol Sci 2016 Feb;37(2):227-34. Epub 2015 Oct 16 doi: 10.1007/s10072-015-2395-7. PMID: 26474874
Poewe W, Hauser RA, Lang A; ADAGIO Investigators.
Mov Disord 2015 Apr;30(4):589-92. Epub 2014 Dec 27 doi: 10.1002/mds.26124. PMID: 25545629
Poewe W, Seppi K, Fitzer-Attas CJ, Wenning GK, Gilman S, Low PA, Giladi N, Barone P, Sampaio C, Eyal E, Rascol O; Rasagiline-for-MSA investigators.
Lancet Neurol 2015 Feb;14(2):145-52. Epub 2014 Dec 8 doi: 10.1016/S1474-4422(14)70288-1. PMID: 25498732
Elmer LW
Parkinsonism Relat Disord 2013 Nov;19(11):930-6. Epub 2013 Jul 10 doi: 10.1016/j.parkreldis.2013.06.001. PMID: 23849501

Therapy

Panisset M, Stril JL, Bélanger M, Lehoux G, Coffin D, Chouinard S
Can J Neurol Sci 2016 Nov;43(6):809-814. doi: 10.1017/cjn.2016.289. PMID: 27827298
Nuebling G, Hensler M, Paul S, Zwergal A, Crispin A, Lorenzl S
J Neurol 2016 Aug;263(8):1565-74. Epub 2016 May 26 doi: 10.1007/s00415-016-8169-1. PMID: 27230855
Masellis M, Collinson S, Freeman N, Tampakeras M, Levy J, Tchelet A, Eyal E, Berkovich E, Eliaz RE, Abler V, Grossman I, Fitzer-Attas C, Tiwari A, Hayden MR, Kennedy JL, Lang AE, Knight J; ADAGIO investigators.
Brain 2016 Jul;139(Pt 7):2050-62. Epub 2016 May 13 doi: 10.1093/brain/aww109. PMID: 27190009
Haehner A, Habersack A, Wienecke M, Storch A, Reichmann H, Hummel T
J Neural Transm (Vienna) 2015 Nov;122(11):1541-6. Epub 2015 Jul 30 doi: 10.1007/s00702-015-1433-1. PMID: 26224038
Macchi Z, Wang Y, Moore D, Katz J, Saperstein D, Walk D, Simpson E, Genge A, Bertorini T, Fernandes JA, Swenson A, Elman L, Dimachkie M, Herbelin L, Miller J, Lu J, Wilkins H, Swerdlow RH, Statland J, Barohn R; Western ALS (WALS) Rasagiline Study Group.
Amyotroph Lateral Scler Frontotemporal Degener 2015;16(5-6):345-52. Epub 2015 Apr 2 doi: 10.3109/21678421.2015.1026826. PMID: 25832828Free PMC Article

Prognosis

Nuebling G, Hensler M, Paul S, Zwergal A, Crispin A, Lorenzl S
J Neurol 2016 Aug;263(8):1565-74. Epub 2016 May 26 doi: 10.1007/s00415-016-8169-1. PMID: 27230855
Masellis M, Collinson S, Freeman N, Tampakeras M, Levy J, Tchelet A, Eyal E, Berkovich E, Eliaz RE, Abler V, Grossman I, Fitzer-Attas C, Tiwari A, Hayden MR, Kennedy JL, Lang AE, Knight J; ADAGIO investigators.
Brain 2016 Jul;139(Pt 7):2050-62. Epub 2016 May 13 doi: 10.1093/brain/aww109. PMID: 27190009
Lim TT, Kluger BM, Rodriguez RL, Malaty IA, Palacio R Jr, Ojo OO, Patel S, Gujrati Y, Nutter B, Swartz C, Hennessy C, Fernandez HH
Mov Disord 2015 Nov;30(13):1825-30. doi: 10.1002/mds.26429. PMID: 26769459
Poewe W, Hauser RA, Lang A; ADAGIO Investigators.
Mov Disord 2015 Apr;30(4):589-92. Epub 2014 Dec 27 doi: 10.1002/mds.26124. PMID: 25545629
Müller T
Expert Opin Drug Metab Toxicol 2014 Oct;10(10):1423-32. Epub 2014 Sep 6 doi: 10.1517/17425255.2014.943182. PMID: 25196265

Clinical prediction guides

Panisset M, Stril JL, Bélanger M, Lehoux G, Coffin D, Chouinard S
Can J Neurol Sci 2016 Nov;43(6):809-814. doi: 10.1017/cjn.2016.289. PMID: 27827298
Cibulcik F, Benetin J, Kurca E, Grofik M, Dvorak M, Richter D, Donath V, Kothaj J, Minar M, Valkovic P
Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub 2016 Dec;160(4):549-552. Epub 2016 Apr 21 doi: 10.5507/bp.2016.023. PMID: 27108605
Hauser RA, Abler V, Eyal E, Eliaz RE
Int J Neurosci 2016 Oct;126(10):942-6. Epub 2016 Mar 18 doi: 10.3109/00207454.2016.1154552. PMID: 26988747
Chen X, Zhao Q, Jiang J, Liu J, Hu P
Clin Drug Investig 2016 May;36(5):369-76. doi: 10.1007/s40261-016-0380-4. PMID: 26951202
Barone P, Santangelo G, Morgante L, Onofrj M, Meco G, Abbruzzese G, Bonuccelli U, Cossu G, Pezzoli G, Stanzione P, Lopiano L, Antonini A, Tinazzi M
Eur J Neurol 2015 Aug;22(8):1184-91. Epub 2015 May 12 doi: 10.1111/ene.12724. PMID: 25962410Free PMC Article

Recent systematic reviews

Hauser RA, Abler V, Eyal E, Eliaz RE
Int J Neurosci 2016 Oct;126(10):942-6. Epub 2016 Mar 18 doi: 10.3109/00207454.2016.1154552. PMID: 26988747
Cai JP, Chen WJ, Lin Y, Cai B, Wang N
Eur Neurol 2015;73(1-2):5-12. Epub 2014 Oct 29 doi: 10.1159/000367892. PMID: 25358603
Müller T
Expert Opin Drug Metab Toxicol 2014 Oct;10(10):1423-32. Epub 2014 Sep 6 doi: 10.1517/17425255.2014.943182. PMID: 25196265
Mínguez-Mínguez S, Solís-García Del Pozo J, Jordán J
Pharmacol Res 2013 Aug;74:78-86. Epub 2013 Jun 2 doi: 10.1016/j.phrs.2013.05.005. PMID: 23735235
Solís-García del Pozo J, Mínguez-Mínguez S, de Groot PW, Jordán J
Expert Opin Drug Saf 2013 Jul;12(4):479-86. Epub 2013 May 2 doi: 10.1517/14740338.2013.790956. PMID: 23634791

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