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Items: 18

1.

Hypertrophy

Abnormal enlargement of a body part or organ. [from NCI]

MedGen UID:
5703
Concept ID:
C0020564
Pathologic Function
2.

Left

Being located on the left side of the body. [from HPO]

MedGen UID:
618170
Concept ID:
C0443246
Spatial Concept
3.

Regression

Return to a former state; a subsidence of the symptoms of a disease process; in cancer, a decrease in the size of a tumor or in the extent of cancer in the body. [from NCI]

MedGen UID:
195771
Concept ID:
C0684320
Pathologic Function
4.

Cardiomegaly - hypertensive

Abnormal enlargement of the heart resulting from long-standing hypertension. [from NCI]

MedGen UID:
151958
Concept ID:
C0694541
Disease or Syndrome
5.

Chronic

Slow, creeping onset, slow progress and long continuance of disease manifestations. [from HPO]

MedGen UID:
104657
Concept ID:
C0205191
Temporal Concept
6.

Ventricular hypertrophy

Enlargement of the cardiac ventricular muscle tissue with increase in the width of the wall of the ventricle and loss of elasticity. Ventricular hypertrophy is clinically differentiated into left and right ventricular hypertrophy. [from HPO]

MedGen UID:
87400
Concept ID:
C0340279
Disease or Syndrome
7.

Left ventricular hypertrophy

Enlargement of the LEFT VENTRICLE of the heart. This increase in ventricular mass is attributed to sustained abnormal pressure or volume loads and is a contributor to cardiovascular morbidity and mortality. [from MeSH]

MedGen UID:
57442
Concept ID:
C0149721
Disease or Syndrome
8.

Isodinit

MedGen UID:
195892
Concept ID:
C0699423
Organic Chemical; Pharmacologic Substance
9.

Dilatrate

MedGen UID:
195891
Concept ID:
C0699421
Organic Chemical; Pharmacologic Substance
10.

Isordil

MedGen UID:
154416
Concept ID:
C0590720
Organic Chemical; Pharmacologic Substance
11.

Isoket

MedGen UID:
154415
Concept ID:
C0590717
Organic Chemical; Pharmacologic Substance
12.

Sorbonit

MedGen UID:
148501
Concept ID:
C0699426
Organic Chemical; Pharmacologic Substance
13.

Iso-Bid

MedGen UID:
148499
Concept ID:
C0699422
Organic Chemical; Pharmacologic Substance
14.

Nitrosorbide

MedGen UID:
147005
Concept ID:
C0699425
Organic Chemical; Pharmacologic Substance
15.

Sorbitrate

MedGen UID:
108462
Concept ID:
C0590730
Organic Chemical; Pharmacologic Substance
16.

Isotrate

MedGen UID:
107963
Concept ID:
C0590694
Organic Chemical; Pharmacologic Substance
17.

Dianhydrosorbitol

MedGen UID:
76389
Concept ID:
C0282212
Organic Chemical; Pharmacologic Substance
18.

Isosorbide mononitrate

The mononitrate salt form of isosorbide, an organic nitrate with vasodilator activity. Isosorbide mononitrate relaxes vascular smooth muscle by formation of the free radical nitric oxide (NO), which is identical to the endothelium-derived relaxing factor (EDRF). NO activates guanylyl cyclase, thereby increasing the synthesis of cGMP within smooth muscle, resulting in dephosphorylation of light chain myosin and relaxation of peripheral arteries and veins. In addition, isosorbide mononitrate relaxes coronary arteries, thereby increasing the blood circulation through the ischemic area. (NCI05) [from NCI]

MedGen UID:
17155
Concept ID:
C0064079
Organic Chemical; Pharmacologic Substance
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