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Drowsiness

MedGen UID:
4390
Concept ID:
C0013144
Finding
Synonyms: Sleepy
SNOMED CT: Drowsiness (79519003); Sleepiness (79519003); Drowsiness, function (79519003); Mental status, drowsy (271782001); Somnolence (sleepiness) (271782001); Sleepy (271782001); Drowsiness (271782001); Sleepiness (271782001); Drowsy (271782001)
 
HPO: HP:0002329

Definition

Excessive daytime sleepiness. [from HPO]

Conditions with this feature

Hypervalinemia
MedGen UID:
120652
Concept ID:
C0268573
Disease or Syndrome
An increased concentration of valine in the blood.
Leucine-induced hypoglycemia
MedGen UID:
82888
Concept ID:
C0271714
Disease or Syndrome
Aquagenic epilepsy
MedGen UID:
98286
Concept ID:
C0393729
Disease or Syndrome
Hot water epilepsy (HWE) is a form of reflex or sensory epilepsy in which seizures are precipitated by immersion in hot water or pouring of hot water over the head during bathing. The seizures are usually complex partial, but about 33% of patients experience secondary generalization. There are no additional neurologic abnormalities (Satishchandra, 2003).
Familial hemiplegic migraine type 1
MedGen UID:
331389
Concept ID:
C1832894
Familial hemiplegic migraine (FHM) falls within the category of migraine with aura. In migraine with aura (including familial hemiplegic migraine) the neurologic symptoms of aura are unequivocally localizable to the cerebral cortex or brain stem and include visual disturbance (most common), sensory loss (e.g., numbness or paresthesias of the face or an extremity), and dysphasia (difficulty with speech); FHM must include motor involvement, i.e., hemiparesis (weakness of an extremity). Hemiparesis occurs with at least one other symptom during FHM aura. Neurologic deficits with FHM attacks can be prolonged for hours to days and may outlast the associated migrainous headache. FHM is often earlier in onset than typical migraine, frequently beginning in the first or second decade; the frequency of attacks tends to decrease with age. Approximately 40%-50% of families with FHM1 have cerebellar signs ranging from nystagmus to progressive, usually late-onset mild ataxia. Cerebral infarction and death have rarely been associated with hemiplegic migraine.
Familial hemiplegic migraine type 2
MedGen UID:
355962
Concept ID:
C1865322
Disease or Syndrome
Familial hemiplegic migraine (FHM) falls within the category of migraine with aura. In migraine with aura (including familial hemiplegic migraine) the neurologic symptoms of aura are unequivocally localizable to the cerebral cortex or brain stem and include visual disturbance (most common), sensory loss (e.g., numbness or paresthesias of the face or an extremity), and dysphasia (difficulty with speech); FHM must include motor involvement, i.e., hemiparesis (weakness of an extremity). Hemiparesis occurs with at least one other symptom during FHM aura. Neurologic deficits with FHM attacks can be prolonged for hours to days and may outlast the associated migrainous headache. FHM is often earlier in onset than typical migraine, frequently beginning in the first or second decade; the frequency of attacks tends to decrease with age. Approximately 40%-50% of families with FHM1 have cerebellar signs ranging from nystagmus to progressive, usually late-onset mild ataxia. Cerebral infarction and death have rarely been associated with hemiplegic migraine.
Hypothyroidism, congenital, nongoitrous, 6
MedGen UID:
482447
Concept ID:
C3280817
Disease or Syndrome

Recent clinical studies

Etiology

Gaspar JG, Brown TL, Schwarz CW, Lee JD, Kang J, Higgins JS
Traffic Inj Prev 2017 May 29;18(sup1):S58-S63. Epub 2017 Mar 21 doi: 10.1080/15389588.2017.1303140. PMID: 28323444
Qian D, Wang B, Qing X, Zhang T, Zhang Y, Wang X, Nakamura M
IEEE Trans Biomed Eng 2017 Apr;64(4):743-754. Epub 2016 Jun 1 doi: 10.1109/TBME.2016.2574812. PMID: 27254855
Aidman E, Chadunow C, Johnson K, Reece J
Accid Anal Prev 2015 Aug;81:8-13. Epub 2015 Apr 29 doi: 10.1016/j.aap.2015.03.041. PMID: 25932964
Wilkinson VE, Jackson ML, Westlake J, Stevens B, Barnes M, Swann P, Rajaratnam SM, Howard ME
J Clin Sleep Med 2013 Dec 15;9(12):1315-24. doi: 10.5664/jcsm.3278. PMID: 24340294Free PMC Article
Anderson C, Chang AM, Sullivan JP, Ronda JM, Czeisler CA
J Clin Sleep Med 2013 Sep 15;9(9):907-20, 920A-920B. doi: 10.5664/jcsm.2992. PMID: 23997703Free PMC Article

Diagnosis

Qian D, Wang B, Qing X, Zhang T, Zhang Y, Wang X, Nakamura M
IEEE Trans Biomed Eng 2017 Apr;64(4):743-754. Epub 2016 Jun 1 doi: 10.1109/TBME.2016.2574812. PMID: 27254855
Patrick KC, Imtiaz SA, Bowyer S, Rodriguez-Villegas E
Conf Proc IEEE Eng Med Biol Soc 2016 Aug;2016:3523-3526. doi: 10.1109/EMBC.2016.7591488. PMID: 28269058
Karchani M, Mazloumi A, NaslSaraji G, Akbarzadeh A, Niknezhad A, Ebrahimi MH, Raei M, Khandan M
J Res Health Sci 2015 Fall;15(4):250-5. PMID: 26728912
Wilkinson VE, Jackson ML, Westlake J, Stevens B, Barnes M, Swann P, Rajaratnam SM, Howard ME
J Clin Sleep Med 2013 Dec 15;9(12):1315-24. doi: 10.5664/jcsm.3278. PMID: 24340294Free PMC Article
Anderson C, Chang AM, Sullivan JP, Ronda JM, Czeisler CA
J Clin Sleep Med 2013 Sep 15;9(9):907-20, 920A-920B. doi: 10.5664/jcsm.2992. PMID: 23997703Free PMC Article

Therapy

Gaspar JG, Brown TL, Schwarz CW, Lee JD, Kang J, Higgins JS
Traffic Inj Prev 2017 May 29;18(sup1):S58-S63. Epub 2017 Mar 21 doi: 10.1080/15389588.2017.1303140. PMID: 28323444
François C, Hoyoux T, Langohr T, Wertz J, Verly JG
Int J Environ Res Public Health 2016 Jan 29;13(2):174. doi: 10.3390/ijerph13020174. PMID: 26840325Free PMC Article
Karchani M, Mazloumi A, NaslSaraji G, Akbarzadeh A, Niknezhad A, Ebrahimi MH, Raei M, Khandan M
J Res Health Sci 2015 Fall;15(4):250-5. PMID: 26728912
Aidman E, Chadunow C, Johnson K, Reece J
Accid Anal Prev 2015 Aug;81:8-13. Epub 2015 Apr 29 doi: 10.1016/j.aap.2015.03.041. PMID: 25932964
Anderson C, Chang AM, Sullivan JP, Ronda JM, Czeisler CA
J Clin Sleep Med 2013 Sep 15;9(9):907-20, 920A-920B. doi: 10.5664/jcsm.2992. PMID: 23997703Free PMC Article

Prognosis

Vicente J, Laguna P, Bartra A, Bailón R
Med Biol Eng Comput 2016 Jun;54(6):927-37. Epub 2016 Jan 16 doi: 10.1007/s11517-015-1448-7. PMID: 26780463
Wang X, Xu C
Accid Anal Prev 2016 Oct;95(Pt B):350-7. Epub 2015 Oct 1 doi: 10.1016/j.aap.2015.09.002. PMID: 26433567
Karchani M, Mazloumi A, NaslSaraji G, Akbarzadeh A, Niknezhad A, Ebrahimi MH, Raei M, Khandan M
J Res Health Sci 2015 Fall;15(4):250-5. PMID: 26728912
McDonald AD, Lee JD, Schwarz C, Brown TL
Hum Factors 2014 Aug;56(5):986-98. doi: 10.1177/0018720813515272. PMID: 25141601
Anderson C, Chang AM, Sullivan JP, Ronda JM, Czeisler CA
J Clin Sleep Med 2013 Sep 15;9(9):907-20, 920A-920B. doi: 10.5664/jcsm.2992. PMID: 23997703Free PMC Article

Clinical prediction guides

Vicente J, Laguna P, Bartra A, Bailón R
Med Biol Eng Comput 2016 Jun;54(6):927-37. Epub 2016 Jan 16 doi: 10.1007/s11517-015-1448-7. PMID: 26780463
Karchani M, Mazloumi A, NaslSaraji G, Akbarzadeh A, Niknezhad A, Ebrahimi MH, Raei M, Khandan M
J Res Health Sci 2015 Fall;15(4):250-5. PMID: 26728912
Aidman E, Chadunow C, Johnson K, Reece J
Accid Anal Prev 2015 Aug;81:8-13. Epub 2015 Apr 29 doi: 10.1016/j.aap.2015.03.041. PMID: 25932964
McDonald AD, Lee JD, Schwarz C, Brown TL
Hum Factors 2014 Aug;56(5):986-98. doi: 10.1177/0018720813515272. PMID: 25141601
Anderson C, Chang AM, Sullivan JP, Ronda JM, Czeisler CA
J Clin Sleep Med 2013 Sep 15;9(9):907-20, 920A-920B. doi: 10.5664/jcsm.2992. PMID: 23997703Free PMC Article

Recent systematic reviews

Simon ST, Higginson IJ, Booth S, Harding R, Weingärtner V, Bausewein C
Cochrane Database Syst Rev 2016 Oct 20;10:CD007354. doi: 10.1002/14651858.CD007354.pub3. PMID: 27764523
Wuytack F, Smith V, Cleary BJ
Cochrane Database Syst Rev 2016 Jul 14;7:CD011352. doi: 10.1002/14651858.CD011352.pub2. PMID: 27412362
Boelig RC, Barton SJ, Saccone G, Kelly AJ, Edwards SJ, Berghella V
Cochrane Database Syst Rev 2016 May 11;(5):CD010607. doi: 10.1002/14651858.CD010607.pub2. PMID: 27168518
Klomp T, van Poppel M, Jones L, Lazet J, Di Nisio M, Lagro-Janssen AL
Cochrane Database Syst Rev 2012 Sep 12;(9):CD009351. doi: 10.1002/14651858.CD009351.pub2. PMID: 22972140
Cobaugh DJ, Erdman AR, Booze LL, Scharman EJ, Christianson G, Manoguerra AS, Caravati EM, Chyka PA, Woolf AD, Nelson LS, Troutman WG
Clin Toxicol (Phila) 2007 Dec;45(8):918-42. doi: 10.1080/15563650701665142. PMID: 18163235

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