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Items: 1 to 20 of 22

1.

Glucose

A primary source of energy for living organisms. It is naturally occurring and is found in fruits and other parts of plants in its free state. It is used therapeutically in fluid and nutrient replacement. [from MeSH]

MedGen UID:
42238
Concept ID:
C0017725
Biologically Active Substance; Organic Chemical; Pharmacologic Substance
2.

Insulin resistance

MedGen UID:
43904
Concept ID:
C0021655
Pathologic Function
3.

Metabolic induction

The conversion of an exogenous substance by a biological system resulting in the production on an active metabolite. [from MeSH]

MedGen UID:
7561
Concept ID:
C0025513
Molecular Function
4.

Inflammation

MedGen UID:
7072
Concept ID:
C0021368
Pathologic Function
5.

Gluconeogenic Process

The biosynthesis of new glucose as opposed to that generated by the metabolism of glycogen. Gluconeogenesis occurs mainly in the liver or kidneys, and involves the biosynthesis of glucose from 3-carbon or 4-carbon non-carbohydrate precursors such as amino acids or fats. [from NCI]

MedGen UID:
6621
Concept ID:
C0017715
Molecular Function
6.

Regular insulin

A 51-amino acid pancreatic hormone that plays a major role in the regulation of glucose metabolism, directly by suppressing endogenous glucose production (GLYCOGENOLYSIS; GLUCONEOGENESIS) and indirectly by suppressing GLUCAGON secretion and LIPOLYSIS. Native insulin is a globular protein comprised of a zinc-coordinated hexamer. Each insulin monomer containing two chains, A (21 residues) and B (30 residues), linked by two disulfide bonds. Insulin is used as a drug to control insulin-dependent diabetes mellitus (DIABETES MELLITUS, TYPE 1). [from MeSH]

MedGen UID:
5827
Concept ID:
C0021641
Amino Acid, Peptide, or Protein; Hormone; Pharmacologic Substance
7.

Hyperglycemia

MedGen UID:
5689
Concept ID:
C0020456
Disease or Syndrome; Finding
8.

Independent

MedGen UID:
721426
Concept ID:
C1299583
Finding
9.

Insulin resistance

MedGen UID:
504630
Concept ID:
CN000801
Finding
10.

Sugar

A white crystalline carbohydrate, typically sucrose, used as a sweetener and preservative. [from NCI]

MedGen UID:
69157
Concept ID:
C0242209
Organic Chemical; Pharmacologic Substance
11.

Diabetes mellitus type 2

Type 2 diabetes is a disorder characterized by abnormally high blood sugar levels. In this form of diabetes, the body stops using and making insulin properly. Insulin is a hormone produced in the pancreas that helps regulate blood sugar levels. Specifically, insulin controls how much glucose (a type of sugar) is passed from the blood into cells, where it is used as an energy source. When blood sugar levels are high (such as after a meal), the pancreas releases insulin to move the excess glucose into cells, which reduces the amount of glucose in the blood.Most people who develop type 2 diabetes first have insulin resistance, a condition in which the body's cells use insulin less efficiently than normal. As insulin resistance develops, more and more insulin is needed to keep blood sugar levels in the normal range. To keep up with the increasing need, insulin-producing cells in the pancreas (called beta cells) make larger amounts of insulin. Over time, the beta cells become less able to respond to blood sugar changes, leading to an insulin shortage that prevents the body from reducing blood sugar levels effectively. Most people have some insulin resistance as they age, but inadequate exercise and excessive weight gain make it worse, greatly increasing the likelihood of developing type 2 diabetes.Type 2 diabetes can occur at any age, but it most commonly begins in middle age or later. Signs and symptoms develop slowly over years. They include frequent urination (polyuria), excessive thirst (polydipsia), fatigue, blurred vision, tingling or loss of feeling in the hands and feet (diabetic neuropathy), sores that do not heal well, and weight loss. If blood sugar levels are not controlled through medication or diet, type 2 diabetes can cause long-lasting (chronic) health problems including heart disease and stroke; nerve damage; and damage to the kidneys, eyes, and other parts of the body.
[from GHR]

MedGen UID:
41523
Concept ID:
C0011860
Disease or Syndrome
12.

Postprandial hyperglycemia

MedGen UID:
383702
Concept ID:
C1855520
Finding
13.

Disorder of glucose metabolism

A metabolic disorder characterized by abnormal blood glucose levels. [from NCI]

MedGen UID:
226229
Concept ID:
C1257958
Disease or Syndrome
14.

Carbohydrate Metabolic Process

Processes concerned with the synthesis, breakdown, and oxidation of carbohydrates in the tissues. [from NCI]

MedGen UID:
86224
Concept ID:
C0302820
Molecular Function
15.

Nutritional and Metabolic Diseases

A collective term for nutritional disorders resulting from poor absorption or nutritional imbalance, and metabolic disorders resulting from defects in biosynthesis (ANABOLISM) or breakdown (CATABOLISM) of endogenous substances. [from MeSH]

MedGen UID:
45164
Concept ID:
C0028715
Disease or Syndrome
16.

Metabolic disease

MedGen UID:
44376
Concept ID:
C0025517
Disease or Syndrome
17.

Hyperinsulinemia

MedGen UID:
43779
Concept ID:
C0020459
Disease or Syndrome; Finding
18.

Diabetes mellitus

MedGen UID:
8350
Concept ID:
C0011849
Disease or Syndrome
19.

Disorder of endocrine system

MedGen UID:
4043
Concept ID:
C0014130
Disease or Syndrome
20.

Maturity-onset diabetes of the young, type 13

MedGen UID:
897640
Concept ID:
C4225365
Disease or Syndrome
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