Format
Items per page

Send to:

Choose Destination

Links from PubMed

Items: 1 to 20 of 22

1.

Hepatitis C

MedGen UID:
42425
Concept ID:
C0019196
Disease or Syndrome
2.

Hepatitis

MedGen UID:
5515
Concept ID:
C0019158
Disease or Syndrome
3.

PSI-7977

MedGen UID:
427670
Concept ID:
C2976304
Nucleic Acid, Nucleoside, or Nucleotide; Pharmacologic Substance
4.

BMS-790052

MedGen UID:
421232
Concept ID:
C2933824
Organic Chemical; Pharmacologic Substance
5.

Telaprevir

MedGen UID:
406297
Concept ID:
C1876229
Amino Acid, Peptide, or Protein; Pharmacologic Substance
6.

Noonan syndrome 3

Noonan syndrome (NS) is characterized by characteristic facies, short stature, congenital heart defect, and developmental delay of variable degree. Other findings can include broad or webbed neck, unusual chest shape with superior pectus carinatum and inferior pectus excavatum, cryptorchidism, varied coagulation defects, lymphatic dysplasias, and ocular abnormalities. Although birth length is usually normal, final adult height approaches the lower limit of normal. Congenital heart disease occurs in 50%-80% of individuals. Pulmonary valve stenosis, often with dysplasia, is the most common heart defect and is found in 20%-50% of individuals. Hypertrophic cardiomyopathy, found in 20%-30% of individuals, may be present at birth or develop in infancy or childhood. Other structural defects include atrial and ventricular septal defects, branch pulmonary artery stenosis, and tetralogy of Fallot. Up to one fourth of affected individuals have mild intellectual disability, and language impairments in general are more common in NS than in the general population. [from GeneReviews]

MedGen UID:
349931
Concept ID:
C1860991
Disease or Syndrome
7.

Resistance to hepatitis C virus

MedGen UID:
332112
Concept ID:
C1836031
Finding
8.

Interferon

Human interferons have been classified into 3 groups: alpha, beta, and gamma. Both alpha- and beta-IFNs, previously designated type I, are acid-stable, but they differ immunologically and in regard to some biologic and physiochemical properties. The IFNs produced by virus-stimulated leukocytes (leukocyte IFNs) are predominantly of the alpha type. Those produced by lymphoblastoid cells are about 90% alpha and 10% beta. Induced fibroblasts produce mainly or exclusively the beta type. The alpha- and beta-IFNs differ widely in amino acid sequence. The gamma or immune IFNs, which are produced by T lymphocytes in response to mitogens or to antigens to which they are sensitized, are acid-labile and serologically distinct from alpha- and beta-IFNs. (from OMIM 147570) [from NCI]

MedGen UID:
196514
Concept ID:
C0733470
Amino Acid, Peptide, or Protein; Immunologic Factor; Pharmacologic Substance
9.

Cytotoxicity

The adverse effect of some iatrogenic therapies. It is an accepted side effect in radiation therapy where the desired effect is to kill rapidly growing tumor cells. In the killing of tumor cells, other cells that are rapidly growing e.g hair, mucous membranes are also killed. [from NCI]

MedGen UID:
108579
Concept ID:
C0596402
Cell or Molecular Dysfunction
10.

Peptide hydrolase inhibitor

Any substance that inhibits a protease, an enzyme that breaks peptide bonds. Proteases are required for many cell processes and inhibition of proteases can inhibit viral replication, inflammatory responses, proliferation, and tumor growth. [from NCI]

MedGen UID:
18701
Concept ID:
C0033607
Pharmacologic Substance
11.

Interferon

Proteins secreted by vertebrate cells in response to a wide variety of inducers. They confer resistance against many different viruses, inhibit proliferation of normal and malignant cells, impede multiplication of intracellular parasites, enhance macrophage and granulocyte phagocytosis, augment natural killer cell activity, and show several other immunomodulatory functions. [from MeSH]

MedGen UID:
5847
Concept ID:
C0021747
Amino Acid, Peptide, or Protein; Immunologic Factor; Pharmacologic Substance
12.

Molecular Mechanisms of Pharmacological Action

Pharmacological activities at the molecular level of DRUGS and other exogenous compounds that are used to treat DISEASES and affect normal BIOCHEMISTRY. [from MeSH]

MedGen UID:
226255
Concept ID:
C1258062
Molecular Function
13.

Antimicrobial substance

Generically, any agent that destroys microbes. However, usage of the term is increasingly being confined to agents that prevent or reduce the transmission of SEXUALLY TRANSMITTED DISEASES. [from MeSH]

MedGen UID:
209727
Concept ID:
C1136254
Pharmacologic Substance
14.

Viral Load

The number of viral particles (usually HIV) in a sample of blood plasma.(On-line Medical Dictionary) [from NCI]

MedGen UID:
84035
Concept ID:
C0376705
Finding
15.

Hematoidin

MedGen UID:
9186
Concept ID:
C0018937
Organic Chemical; Pharmacologic Substance
16.

Enzyme inhibitor

Compounds or agents that combine with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction. [from MeSH]

MedGen UID:
8652
Concept ID:
C0014432
Pharmacologic Substance
17.

Antiviral agent

Agents used in the prophylaxis or therapy of VIRUS DISEASES. Some of the ways they may act include preventing viral replication by inhibiting viral DNA polymerase; binding to specific cell-surface receptors and inhibiting viral penetration or uncoating; inhibiting viral protein synthesis; or blocking late stages of virus assembly. [from MeSH]

MedGen UID:
356
Concept ID:
C0003451
Pharmacologic Substance
18.

Anti-infective agent

A pharmacological agent that can kill or prevent the reproduction of infectious organisms. [from NCI]

MedGen UID:
324
Concept ID:
C0003204
Pharmacologic Substance
19.

Daklinza

MedGen UID:
1391264
Concept ID:
C4046850
Organic Chemical; Pharmacologic Substance
20.

Incivek

MedGen UID:
469015
Concept ID:
C3154701
Amino Acid, Peptide, or Protein; Pharmacologic Substance
Format
Items per page

Send to:

Choose Destination

Supplemental Content

Find related data

Recent activity

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...
Support Center