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Items: 6

1.

Dopamine

A monoamine compound with positive inotropic activity. Dopamine is a naturally occurring catecholamine formed by decarboxylation of dehydroxyphenylalanine and a precursor of norepinephrine and epinephrine. Dopamine binds to alpha-1 and beta-1 adrenergic receptors. Mediated through myocardial beta-1 adrenergic receptors, dopamine increase heart rate and force, thereby increasing cardiac output. Alpha-1 adrenergic receptor stimulation on vascular smooth muscle, leads to vasoconstriction and results in an increase in systemic vascular resistance. Stimulation of dopaminergic receptors in renal vasculature, leads to renal blood vessel dilation, and an increase in glomerular filtration rate, renal blood flow, sodium excretion, and urine output. [from NCI]

MedGen UID:
41644
Concept ID:
C0013030
Biologically Active Substance; Organic Chemical; Pharmacologic Substance
2.

Receptor Antagonists, Dopamine D2

Compounds and drugs that bind to and inhibit or block the activation of DOPAMINE D2 RECEPTORS. [from MeSH]

MedGen UID:
827193
Concept ID:
C3850099
Pharmacologic Substance
3.

Drug Partial Agonism

Drug agonism involving selective binding but reduced effect. This can result in some degree of DRUG ANTAGONISM. [from MeSH]

MedGen UID:
408204
Concept ID:
C1955892
Molecular Function
4.

Drug Agonism

Phenomena and pharmaceutics of compounds that selectively bind to a specific receptor and trigger a response. They mimic the action of endogenous biochemical molecules. Their effect can be countered by antagonists (DRUG ANTAGONISM). [from MeSH]

MedGen UID:
363050
Concept ID:
C1955883
Molecular Function
5.

Endemic Tyrolean Infantile Cirrhosis

MedGen UID:
360291
Concept ID:
C1876166
Disease or Syndrome
6.

Eticlopride

MedGen UID:
28905
Concept ID:
C0059853
Organic Chemical; Pharmacologic Substance
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